Evidence map›Paper›PMID 41041108›Full record

ArticleCureus2025

Unilateral Vibration Stimulation in Patients With Post-stroke Spasticity Suppresses Muscle Tonus in the Contralateral Homologous Muscles.

Kenta Kunoh, Takahiro Takenaka, Daisuke Kimura, Toshiaki Suzuki

Registry-linked trialAbstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07321158 (The Effectiveness of High Versus Low Pulse Duration Neuromuscular Electrical Stimulation), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07321158 narecruitingnot on this mapstarted 2026, after this paper: background citation

The Effectiveness of High Versus Low Pulse Duration Neuromuscular Electrical Stimulation (NMES) in Patients With Upper Limb Pyramidal Tract-related Spasticity Measured by Neurophysiological Tools: A Randomized Controlled Trial

TypeinterventionalSponsorUniversity of West AtticaRan2026 to 2026Enrolled45ConditionsPyramidal Tract-related Spasticity, Upper Motor Neuron LesionArmsHigh Pulse Duration Neuromuscular Electrical Stimulation Group, Low Pulse Duration Neuromuscular Electrical Stimulation Group, Usual Care Group
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kenta KunohDepartment of Health Sciences, Graduate School of Health Sciences, Kansai University of Health Sciences, Osaka, JPN.
Takahiro TakenakaDepartment of Rehabilitation, Heisei College of Health Sciences, Gifu, JPN.
Daisuke KimuraDivision of Occupational Therapy, Naragakuen University, Nara, JPN.
Toshiaki SuzukiDepartment of Health Sciences, Graduate School of Health Sciences, Kansai University of Health Sciences, Osaka, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to examine whether unilateral vibration stimulation can reduce spasticity during the stimulation period in post-stroke patients.

methodsTen post-stroke patients with increased muscle tone in the flexor carpi radialis (FCR) participated. Vibration stimulation at 80 Hz was applied to the paretic-side FCR. The H-reflex and muscle stiffness were assessed before, during, and immediately after stimulation. Changes in H-reflex parameters were analyzed alongside muscle stiffness using the Wilcoxon signed-rank test.

resultsH-reflex measurements showed a temporary reduction in spasticity during stimulation. However, no significant change was observed in muscle stiffness.

conclusionUnilateral vibration stimulation may offer immediate neurophysiological suppression of spasticity during application, although it does not appear to affect muscle stiffness in the short term. These findings suggest potential for use as a complementary intervention in stroke rehabilitation.

Indexed as

h-reflexmuscle stiffnessspasticitystrokevibration

Identifiers

PMID41041108
PMCPMC12484244

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.