Evidence map›Paper›PMID 41041047›Full record

ArticleTheranostics2025

Transcriptomic Profiling of the Tumor Immune Microenvironment Reveals Prognostic Markers in mCRPC Patients Treated with LuPSMA Therapy.

Analena Handke, Leonor Lopes, Claudia Kesch, Christopher Darr, Elai Davicioni, Kuangyu Shi, Tugce Telli, Wolfgang P Fendler, Ken Herrmann, Katharina Lückerath and 2 more

Abstract read
In one paragraph

Article in Theranostics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Analena HandkeDepartment of Urology, University of Duisburg-Essen and German Cancer Consortium (DKTK), University Medicine Essen, Essen, Germany.
Leonor LopesDepartment of Nuclear Medicine, University Hospital Bern, Inselspital, University of Bern, Bern, Switzerland.
Claudia KeschDepartment of Urology, University of Duisburg-Essen and German Cancer Consortium (DKTK), University Medicine Essen, Essen, Germany.
Christopher DarrDepartment of Urology, University of Duisburg-Essen and German Cancer Consortium (DKTK), University Medicine Essen, Essen, Germany.
Elai DavicioniVeracyte, Inc, San Diego, California, USA.
Kuangyu ShiDepartment of Nuclear Medicine, University Hospital Bern, Inselspital, University of Bern, Bern, Switzerland.
Tugce TelliDepartment of Nuclear Medicine, University of Duisburg-Essen and German Cancer Consortium, (DKTK)-University Medicine Essen, Essen, Germany.
Wolfgang P FendlerDepartment of Nuclear Medicine, University of Duisburg-Essen and German Cancer Consortium, (DKTK)-University Medicine Essen, Essen, Germany.
Ken HerrmannDepartment of Nuclear Medicine, University of Duisburg-Essen and German Cancer Consortium, (DKTK)-University Medicine Essen, Essen, Germany.
Katharina LückerathDepartment of Nuclear Medicine, University of Duisburg-Essen and German Cancer Consortium, (DKTK)-University Medicine Essen, Essen, Germany.
Boris HadaschikDepartment of Urology, University of Duisburg-Essen and German Cancer Consortium (DKTK), University Medicine Essen, Essen, Germany.
Robert SeifertDepartment of Nuclear Medicine, University of Duisburg-Essen and German Cancer Consortium, (DKTK)-University Medicine Essen, Essen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Tumor MicroenvironmentAgedBiomarkers, TumorGene Expression ProfilingHumansMaleMiddle AgedPrognosisTranscriptomeBiomarkers, Tumor[177Lu]Lu-PSMA-617 therapyDecipher prostate assayPD-L2.prostate cancertranscriptomic profiling

Identifiers

PMID41041047
PMCPMC12486015

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.