Evidence map›Paper›PMID 41041045›Full record

ArticleTheranostics2025

Luminal Stem-like Cells in High-Risk/Locally Advanced Prostate Cancer Promote Resistance to Hormonal Therapy.

Guyu Tang, Jing Liu, Xiaomei Gao, Kai Yuan, Minfeng Chen, Long Wang, Lin Qi, Yi Cai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Guyu TangDepartment of Urology, the Third Xiangya Hospital, Central South University; Postdoctoral Station of Basic Medicine, the Third Xiangya Hospital, Central South University, Changsha, China; Center for Experimental Medicine, the Third Xiangya Hospital, Central South University; Disease Genome Research Center, Central South University, Changsha City, 410013, Hunan Province, P.R. China.
Jing LiuDepartment of PET/CT Center, Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, No.283 Tongzipo Road, Changsha City, 410013, Hunan Province, P.R. China.
Xiaomei GaoDepartment of Pathology, Xiangya Hospital of Central South University, No.87 Xiangya Road, Changsha City, 410008, Hunan Province, P.R. China.
Kai YuanHunan Key Laboratory of Molecular Precision Medicine, Department of Oncology, Xiangya Hospital, Central South University, No.87 Xiangya Road, Changsha City, 410008, Hunan Province, P.R. China.
Minfeng ChenDepartment of Urology, Disorders of Prostate Cancer Multidisciplinary Team, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, No.87 Xiangya Road, Changsha City, 410008, Hunan Province, P.R. China.
Long WangDepartment of Urology, the Third Xiangya Hospital, Central South University; Postdoctoral Station of Basic Medicine, the Third Xiangya Hospital, Central South University, Changsha, China; Center for Experimental Medicine, the Third Xiangya Hospital, Central South University; Disease Genome Research Center, Central South University, Changsha City, 410013, Hunan Province, P.R. China.
Lin QiDepartment of Urology, Disorders of Prostate Cancer Multidisciplinary Team, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, No.87 Xiangya Road, Changsha City, 410008, Hunan Province, P.R. China.
Yi CaiDepartment of Urology, Disorders of Prostate Cancer Multidisciplinary Team, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, No.87 Xiangya Road, Changsha City, 410008, Hunan Province, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antineoplastic Agents, HormonalDrug Resistance, NeoplasmNeoplastic Stem CellsProstatic NeoplasmsAgedAndrogen AntagonistsEpithelial CellsHumansMaleNeoplasm Recurrence, LocalOrganoidsSingle-Cell AnalysisSOX9 Transcription FactorTumor MicroenvironmentAndrogen AntagonistsAntineoplastic Agents, HormonalSOX9 protein, humanSOX9 Transcription Factorhigh-risk/locally advanced prostate cancerhormonal therapypatient-derived organoidssingle-cell RNA sequencingstem-like cellstumor microenvironment

Identifiers

PMID41041045
PMCPMC12486265

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.