Evidence map›Paper›PMID 41041044›Full record

ArticleTheranostics2025

Bone remodeling stimulated by Wnt-mediated mitophagy regulated extracellular vesicles in subchondral bone contributes to osteoarthritis development.

Yuyuan Gu, Qirong Zhou, Shihao Sheng, Huijian Yang, Dan Huang, Qin Zhang, Hao Zhang, Zijian Cao, Yuanwei Zhang, Zuhao Li and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Yuyuan GuDepartment of Orthopedics, Xinhua Hospital Affiliated to Shanghai JiaoTong University School of Medicine, Shanghai 200092, P. R. China.
Qirong ZhouDepartment of Orthopedics, Xinhua Hospital Affiliated to Shanghai JiaoTong University School of Medicine, Shanghai 200092, P. R. China.
Shihao ShengDepartment of Orthopedics, Xinhua Hospital Affiliated to Shanghai JiaoTong University School of Medicine, Shanghai 200092, P. R. China.
Huijian YangInstitute of Translational Medicine, Shanghai University, Shanghai 200444, P. R. China.
Dan HuangInstitute of Translational Medicine, Shanghai University, Shanghai 200444, P. R. China.
Qin ZhangInstitute of Translational Medicine, Shanghai University, Shanghai 200444, P. R. China.
Hao ZhangDepartment of Orthopedics, Xinhua Hospital Affiliated to Shanghai JiaoTong University School of Medicine, Shanghai 200092, P. R. China.
Zijian CaoDepartment of Orthopedics, People's Liberation Army Joint Logistic Support Force 920th Hospital, Kunming City, Yunnan 650032, P. R. China.
Yuanwei ZhangDepartment of Orthopedics, Xinhua Hospital Affiliated to Shanghai JiaoTong University School of Medicine, Shanghai 200092, P. R. China.
Zuhao LiDepartment of Orthopedics, Xinhua Hospital Affiliated to Shanghai JiaoTong University School of Medicine, Shanghai 200092, P. R. China.
Yingying JiangInstitute of Translational Medicine, Shanghai University, Shanghai 200444, P. R. China.
Xiao ChenDepartment of Orthopedics, Xinhua Hospital Affiliated to Shanghai JiaoTong University School of Medicine, Shanghai 200092, P. R. China.
Yingying JingInstitute of Translational Medicine, Shanghai University, Shanghai 200444, P. R. China.
Chenglong WangDepartment of Orthopedics, Xinhua Hospital Affiliated to Shanghai JiaoTong University School of Medicine, Shanghai 200092, P. R. China.
Hongbo TanDepartment of Orthopedics, People's Liberation Army Joint Logistic Support Force 920th Hospital, Kunming City, Yunnan 650032, P. R. China.
Ke XuInstitute of Translational Medicine, Shanghai University, Shanghai 200444, P. R. China.
Jiacan SuDepartment of Orthopedics, Xinhua Hospital Affiliated to Shanghai JiaoTong University School of Medicine, Shanghai 200092, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bone RemodelingExtracellular VesiclesMitophagyOsteoarthritisAnimalsCell DifferentiationDisease Models, AnimalHumansMaleMesenchymal Stem CellsMiceMice, Inbred C57BLMicroRNAsOsteoblastsOsteogenesisWnt ProteinsMicroRNAsWnt Proteinsextracellular vesiclesmitophagyosteoarthritisosteoblastsubchondral bone

Identifiers

PMID41041044
PMCPMC12486141

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.