ArticleInternational journal of clinical pediatric dentistry2025
Papillon-Lefèvre Syndrome: Case Report of Two Sisters.
Article in International journal of clinical pediatric dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Papillon-Lefèvre syndrome (PLS), also known as keratosis palmoplantaris with periodontopathia and "hyperkeratosis palmoplantaris with periodontosis," is a rare autosomal recessive disorder, characterized by diffuse palmoplantar keratoderma and precocious aggressive periodontitis, leading to premature loss of deciduous and permanent dentition at a very young age. The aim of this article is to revisit PLS, address its diagnosis update and dental management, and to provide insight into the fascinating role of consanguinity in the etiology of this unusual illness. We report the case of two Moroccan sisters aged 5 and 8 years old with PLS who consulted the pedodontics department at the CCTD in Rabat, Morocco, for the early loss of teeth. How to cite this article: El-Missioui A, Benkarroum FZ, Ramdi H. Papillon-Lefèvre Syndrome: Case Report of Two Sisters. Int J Clin Pediatr Dent 2025;18(6):733-737.
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