ArticleJournal of inflammation research2025
Decreasing Procalcitonin and Its Ratio to Albumin Predict Mortality in Patients with Abdominal Sepsis.
Article in Journal of inflammation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Purpose: Abdominal sepsis may act as a life-threatening disease characterized by a dysregulated inflammatory response and nutritional deficits. Given the complex interplay between inflammation and malnutrition, integrating these biomarkers may provide a more comprehensive understanding of patients' outcomes and improve early prognosis in the intensive care unit (ICU). Herein, we report the predictive value of procalcitonin (PCT) and its ratio to albumin (ALB) for mortality of abdominal sepsis patients, aiming to provide more references for clinical disease management. Patients and Methods: This is a retrospective study involving one hundred and twenty-four patients diagnosed with abdominal sepsis. Kaplan-Meier survival analysis was utilized to analyze the 30- and 90-day mortality of patients. Univariable and multivariable Cox regression analyses were conducted to confirm the prognostic factors. In addition, ROC analyses were performed to evaluate the diagnostic efficiency. Results: An 80% decrease of PCT within 4 days was identified as a cutoff to predict the 30-day ( Conclusion: In conclusion, the decrease in PCT and the ratio of PCT decrease/ALB are promising biomarkers to predict mortality in patients with abdominal sepsis.
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