Evidence map›Paper›PMID 41040983›Full record

ArticleFrontiers in cellular and infection microbiology2025

Single radiation exposure induces gut microbiota dysbiosis and decreases short-chain fatty acid metabolism and intestinal barrier integrity in mice.

Mineon Park, You Yeon Choi, Yanghee Lee, Minsu Cho

Erratum issuedAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Gut Microbiota Dysbiosis MediatesImmunity, inflammation and disease · 2026
    Article
  3. Review
  4. [Mechanisms of live combinedZhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2026
    Article
  5. Review
  6. Review
  7. Feline-DerivedMicroorganisms · 2026
    Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Mineon ParkLaboratory of Biological Dosimetry, National Radiation Emergency Medical Center, Korea Institute of Radiological & Medical Sciences (KIRAMS), Seoul, Republic of Korea.
You Yeon Choi *Department of Convergence Korean Medical Science, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.
Yanghee Lee *Laboratory of Biological Dosimetry, National Radiation Emergency Medical Center, Korea Institute of Radiological & Medical Sciences (KIRAMS), Seoul, Republic of Korea.
Minsu ChoLaboratory of Biological Dosimetry, National Radiation Emergency Medical Center, Korea Institute of Radiological & Medical Sciences (KIRAMS), Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ionizing radiation causes biological damage, including DNA damage, inflammation, and tissue homeostasis disruption. The gastrointestinal tract, which harbors diverse gut microbiota, is particularly susceptible to radiation-induced injury and intestinal barrier dysfunction. We aimed to investigate the effects of single and fractionated radiation exposures on gut microbiota diversity and short-chain fatty acid (SCFA) metabolism. Mice were exposed to a single dose (1 Gy, one exposure; dose rate: 2.6 Gy/min) or fractionated doses (1 Gy accumulated over 75 fractions, 6.7 mGy/min for 2 min per session).

Indexed as

DysbiosisFatty Acids, VolatileGastrointestinal MicrobiomeIntestinal MucosaRadiation ExposureAnimalsCaco-2 CellsCytokinesDNA DamageHumansMaleMiceMice, Inbred C57BLReactive Oxygen SpeciesReceptors, G-Protein-CoupledTight JunctionsCytokinesFatty Acids, VolatileFfar2 protein, mouseReactive Oxygen SpeciesReceptors, G-Protein-Coupleddysbiosisgut microbiotaintestinal barrier dysfunctionSCFAssingle and fractionated radiation responses

Identifiers

PMID41040983
PMCPMC12484129

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.