ArticleJournal of surgical case reports2025
Palliative cholangiojejunostomy for refractory biliary obstruction in mucinous cholangiocarcinoma: a case report.
Article in Journal of surgical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Mucinous cholangiocarcinoma is a rare, aggressive biliary tract malignancy. Excessive mucin secretion causes diagnostic and therapeutic challenges. A 76-year-old male presented with painless progressive jaundice. Imaging showed cystic lesions with calcification in the right liver/hilum, intrahepatic bile duct dilation, and stones. Radical resection was deemed unfeasible due to insufficient predicted residual liver volume. Given the high risk of mucin-induced obstruction with conventional biliary drainage, palliative choledochojejunostomy was performed. Intraoperative findings revealed mucin and stones; frozen section pathology confirmed biliary mucinous adenocarcinoma. Postoperatively, bilirubin decreased significantly and biliary dilation improved. Mucinous cholangiocarcinoma management requires a multidisciplinary approach. When radical resection is contraindicated, palliative choledochojejunostomy effectively relieves mucin-related obstruction. Long-term outcomes depend on adjuvant therapy and surveillance; further, molecular research is needed to develop targeted therapies.
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