ArticlePatterns (New York, N.Y.)2025
Achieving handle-level random access in an encrypted DNA archival storage system via frequency dictionary mapping coding.
Article in Patterns (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed.
- Highly biased DNA sequence reconstruction in DNA storage with multi-scale attention mechanism and contrast learning.Synthetic and systems biotechnology · 2026Article
- Predicting protein-protein interaction sites based on dynamic perception mechanism within a hierarchical E(n)-equivariant graph.Briefings in bioinformatics · 2026Article
- DVOUG enables robust DNA sequence assembly and reconstruction with a dynamic, variable-order graph.Cell reports methods · 2025Article
- DNA StairLoop: enabling high-fidelity data recovery and robust error correction in DNA-based data storage.Nature communications · 2025Article
- Achieving handle-level random access in an encrypted DNA archival storage system via frequency dictionary mapping coding.Patterns (New York, N.Y.) · 2025Article
- TGF-M: Topology-augmented geometric features enhance molecular property prediction.PLoS computational biology · 2025Article
- INNSE: Invertible neural network-based DNA image storage with self-correction encoding.Computational and structural biotechnology journal · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
DNA storage provides a high storage density and durability, but current systems experience high latency and lack data security. This study proposed the use of frequency dictionary mapping coding (FDMC) to enable handle-level random access of DNA archival storage. In addition, a hybrid e-molecular encryption strategy and a multi-level error-correction algorithm were introduced to ensure data security and integrity. The simulation and wet experiment results demonstrated that FDMC achieved handle-level random access in a lossless encrypted DNA storage system, which balanced security and robustness. Even in extreme cases, in which there was a 10% loss of DNA sequences, this system still recovered 91.74% of the original data while ensuring a storage density above 1.80 bits per nucleotide. In summary, FDMC enhances the application potential of DNA as a storage medium and bridges the gap between DNA storage and traditional storage modes.
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Registered trials
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