ArticleFrontiers in psychiatry2025
Establishment of local norms and standardization of the MATRICS consensus cognitive battery in Chinese adolescents.
Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Accelerated Magnetic Seizure Therapy for Non-Suicidal Self-Injury in Adolescents With Bipolar Depression.CNS neuroscience & therapeutics · 2026Article
- Blunted niacin skin flushing response with subtype-specific clinical associations in adolescent bipolar disorder.BMC psychiatry · 2026Article
- A transdiagnostic network analysis of psychosocial-clinical-cognitive functioning in young people with bipolar and major depressive disorders.Frontiers in psychiatry · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The MATRICS Consensus Cognitive Battery (MCCB) is a widely used, standardized tool for assessing cognitive impairments in schizophrenia clinical trials. However, normative data for the MCCB in healthy adolescents remain scarce. This study establishes the first regionally representative norms for the MCCB in Chinese adolescents aged 11-16 years. Methods: Using stratified cluster sampling, we recruited 1,244 participants from Xiaogan City, demographically matched to regional population statistics. The Chinese-adapted MCCB assessed seven cognitive domains through nine subtests. Comprehensive analyses evaluated age, gender, and education effects using ANCOVA and non-parametric tests for non-normal distributions. Results: Our analyses revealed distinct developmental patterns across cognitive domains. Significant age-related improvements emerged in most measures (all p<0.05 except Trail Making Test-Part A), demonstrating continuous rather than stage-like progression. Gender differences were observed, with males outperforming in cognitive domains of processing speed, reasoning and problem solving, working memory and attention/vigilance, while females showed advantages in visual learning. After adjusting for gender, age initially exhibited significant associations with all cognitive tests; however, upon further adjustment for education, the effect of age was no longer significant in eight of the nine tests. Conclusion: This study establishes the first locally representative normative standards for the MCCB in Chinese adolescents, addressing a crucial gap in culturally sensitive cognitive assessment tools. Our findings demonstrate the complex interplay of age, gender, and educational factors in cognitive development, providing clinically valuable benchmarks for early detection of schizophrenia in this population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.