Evidence map›Paper›PMID 41040937›Full record

ArticleFrontiers in psychiatry2025

Treatment-refractory catatonia in an adolescent with a

Emmanuelle Hodara, Alexis Seegan, Jianling Ji, Alexander Van Speybroeck

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Emmanuelle HodaraDepartment of Psychiatry, Keck School of Medicine of USC, Los Angeles, CA, United States.
Alexis SeeganDepartment of Psychiatry, University of California, Irvine School of Medicine, Irvine, CA, United States.
Jianling JiCenter for Personalized Medicine, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States.
Alexander Van SpeybroeckDepartment of Pediatrics, Children's Hospital of Los Angeles, Los Angeles, CA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the case of an adolescent patient who developed severe, treatment-refractory catatonia with progressive neurological decline over five years following a brief, self-limited acute psychotic episode following a prodromal period emerging at age 11 with disorganized behavior and restricted, stereotyped interests. Her atypical presentation marked by prolonged mutism, function loss, and retrograde amnesia, unresponsive to standard therapies, showed dramatic improvement with a combination of memantine, oxcarbazepine, and electroconvulsive therapy (ECT). Trio-clinical exome sequencing revealed a

Indexed as

case reportcatatoniaelectroconvulsive therapy (ECT)genetic work-upSIK1 candidate varianttreatment-refractory

Identifiers

PMID41040937
PMCPMC12484001

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.