Evidence map›Paper›PMID 41040916›Full record

ArticleRSC advances2025

Design, synthesis, and

Somaia S Abd El-Karim, Yasmin M Syam, Reham M Abdelkader, Mohamed K El-Ashrey, Manal M Anwar

Abstract read
In one paragraph

Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Somaia S Abd El-KarimDepartment of Therapeutic Chemistry, National Research Centre El-Bohouth St. 12262 Cairo Egypt ssabdelkarim@gmail.com manal.hasan52@live.com.ORCID https://orcid.org/0000-0002-3463-3047
Yasmin M SyamDepartment of Therapeutic Chemistry, National Research Centre El-Bohouth St. 12262 Cairo Egypt ssabdelkarim@gmail.com manal.hasan52@live.com.
Reham M AbdelkaderDepartment of Pharmacology and Toxicology, Faculty of Pharmacy and Biotechnology, German University in Cairo Cairo Egypt.
Mohamed K El-AshreyPharmaceutical Chemistry Department, Faculty of Pharmacy, Cairo University Kasr Elini St. Cairo 11562 Egypt.ORCID https://orcid.org/0000-0002-3548-3888
Manal M AnwarDepartment of Therapeutic Chemistry, National Research Centre El-Bohouth St. 12262 Cairo Egypt ssabdelkarim@gmail.com manal.hasan52@live.com.ORCID https://orcid.org/0000-0002-3967-4534

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new series of benzofuran-pyrazole-based analogues, conjugated with different substituted aromatic and heterocyclic ring systems featuring the pharmacophoric fragments of protein kinase suppressors, 3a-d and 4a-d was synthesized as potential antiproliferative agents. All the new analogues were selected by the NCI to screen their antiproliferative activity against sixty human cancer cell lines (NCI60). The 1

Identifiers

PMID41040916
PMCPMC12486440

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.