Evidence map›Paper›PMID 41040901›Full record

ArticlePlastic and reconstructive surgery. Global open2025

The Use of Oxygen Therapy in Management of Mastectomy Flap Ischemia.

Sravya L Chilukuri, Vaibhav Duggal, Amit Elazar, George D Xipoleas

Abstract readCase Reports
In one paragraph

Article in Plastic and reconstructive surgery. Global open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sravya L ChilukuriFrom the Department of Plastic and Reconstructive Surgery, Icahn School of Medicine at Mount Sinai, South Nassau, Oceanside, NY.
Vaibhav DuggalFrom the Department of Plastic and Reconstructive Surgery, Icahn School of Medicine at Mount Sinai, South Nassau, Oceanside, NY.
Amit ElazarFrom the Department of Plastic and Reconstructive Surgery, Icahn School of Medicine at Mount Sinai, South Nassau, Oceanside, NY.
George D XipoleasFrom the Department of Plastic and Reconstructive Surgery, Icahn School of Medicine at Mount Sinai, South Nassau, Oceanside, NY.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxygen plays a major role in wound healing by improving vessel growth and facilitating wound closure. Topical oxygen therapy has been widely accepted as a treatment for diabetic foot ulcers, but its benefit in compromised flaps and grafts in the field of plastic surgery has gained traction. It is possible to decrease flap necrosis and increase viability with topical oxygen therapy. We present a case of a 48-year-old woman who received topical oxygen therapy to treat postmastectomy areas of skin necrosis. As the patient underwent treatment using topical oxygen therapy to the mastectomy flaps, skin demarcation of bilateral breasts continued to improve and eventually completely resolved. This case demonstrated the significant ability of topical oxygen therapy to promote wound healing in flap ischemia.

Identifiers

PMID41040901
PMCPMC12487945

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.