Evidence map›Paper›PMID 41040898›Full record

ArticlePlastic and reconstructive surgery. Global open2025

Early Outcomes Using TIGR Mesh in Direct-to-Implant Breast Reconstruction.

Orr Shauly, Makenna Ash, Shannon Su, Tola Ebunlomo, Melika Deaton, Susan Doh, Joseph S Khouri, Albert Losken

Abstract read
In one paragraph

Article in Plastic and reconstructive surgery. Global open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Orr ShaulyFrom the Division of Plastics and Reconstructive Surgery, Emory University, Atlanta, GA.
Makenna AshDivision of Plastic and Reconstructive Surgery, Emory University School of Medicine, Atlanta, GA.
Shannon SuDivision of Plastic and Reconstructive Surgery, Emory University School of Medicine, Atlanta, GA.
Tola EbunlomoDivision of Plastic and Reconstructive Surgery, Emory University School of Medicine, Atlanta, GA.
Melika DeatonFrom the Division of Plastics and Reconstructive Surgery, Emory University, Atlanta, GA.
Susan DohDivision of Plastic and Reconstructive Surgery, University Hospitals, Cleveland, OH.
Joseph S KhouriDivision of Plastic and Reconstructive Surgery, University Hospitals, Cleveland, OH.
Albert LoskenFrom the Division of Plastics and Reconstructive Surgery, Emory University, Atlanta, GA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Direct-to-implant (DTI) breast reconstruction often uses soft tissue support to improve outcomes and reduce implant migration. Synthetic meshes, such as TIGR Matrix, have emerged as potential alternatives to biological materials due to lower costs and complication rates. This study reviewed early outcomes using TIGR Matrix in immediate DTI reconstruction. Methods: A retrospective chart review was conducted on patients who underwent implant-based reconstruction with TIGR Matrix between November 2023 and June 2024 across 2 institutions. Inclusion criteria included DTI reconstruction with at least 6 months of follow-up. Data collected included demographics, oncological and reconstructive details, comorbidities, and postoperative complications. Statistical analysis was performed using MATLAB with Results: Seventy-one patients (109 breasts) met inclusion criteria. The cohort included 42.2% nipple-sparing, 40.4% skin-sparing, and 11.0% Goldilocks mastectomies. The mean patient age was 52 years. The mean time to first postoperative follow-up was 8.3 days. Major complications included 6 hematomas (5.5%), 3 seromas (2.8%), 2 infections (1.8%), and 3 explantations (2.8%). Eleven (10.1%) patients required reoperation due to complications including infection, necrosis, or residual disease. Minor complications (delayed wound healing, eschar) were observed in 17.4% of breasts. The overall complication rate excluding minor events was 12.8%. Conclusions: TIGR Matrix demonstrates an acceptable early complication profile in DTI breast reconstruction and may serve as a cost-effective alternative to acellular dermal matrices. Additional studies are needed to assess long-term outcomes and comparative effectiveness.

Identifiers

PMID41040898
PMCPMC12487947

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.