Evidence map›Paper›PMID 41040869›Full record

ArticleFrontiers in endocrinology2025

Comparison of conventional ICSI and rescue ICSI in patients without severe male factor and poor oocyte yield.

Mingzhao Li, Wennan Chen, Xia Xue

Abstract readComparative Study
In one paragraph

Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Mingzhao LiThe ART Center, Northwest Women's and Children's Hospital, Xi'an, China.
Wennan ChenThe ART Center, Northwest Women's and Children's Hospital, Xi'an, China.
Xia XueThe ART Center, Northwest Women's and Children's Hospital, Xi'an, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The aim of this study was to explore the effectivity and safety of early rescue intracytoplasmic sperm injection (R-ICSI) in patients with poor oocyte yield and non-severe male factor. Methods: This study was a retrospective cohort analysis which included 604 conventional ICSI cycles and 116 early R-ICSI cycles at the Northwest Women's and Children's Hospital from February 2014 to December 2023. All patients were during their first assisted reproductive technologies (ART) cycle with 3-5 retrieved oocytes. The male partner had normal or mildly impaired sperm parameters. We compared the reproductive outcomes of conventional ICSI and early R-ICSI cycles in such patients. Results: We observed that there were no significant differences in the MII (86.75 versus 85.09%; Conclusions: Despite the higher MPN rate, comparable outcomes can be achieved following early R-ICSI when compared to conventional ICSI for couples with non-severe male factor and poor oocyte yield.

Indexed as

Infertility, MaleOocytesSperm Injections, IntracytoplasmicAdultFemaleHumansMaleOocyte RetrievalPregnancyPregnancy RateRetrospective Studiesc-IVFfertilization failureICSIreproductive outcomesrescue ICSI

Identifiers

PMID41040869
PMCPMC12483924

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.