Evidence map›Paper›PMID 41040820›Full record

ArticleClinical case reports2025

A Rare Case of Blastomycosis in a Psoriasis Patient Treated With Ustekinumab (Stelara).

Fatima Ghaffar, Ahmed Hassan, Masab Ali, Hafiz Noman Ijaz, Sajjad Jameel, Monika Kumari, Muhammad Husnain Ahmad

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fatima GhaffarDepartment of Internal Medicine Southeast Georgia Health System Brunswick Georgia USA.
Ahmed HassanDepartment of Internal Medicine Punjab Medical College Faisalabad Pakistan.
Masab AliDepartment of Internal Medicine Punjab Medical College Faisalabad Pakistan.ORCID https://orcid.org/0009-0007-8599-6861
Hafiz Noman IjazShaikh Khalifa Bin Zayed Al-Nahyan Medical and Dental College Lahore Pakistan.
Sajjad JameelUofL Health-Jewish Hospital Louisville Kentucky USA.
Monika KumariLiaquat National Medical College Karachi Pakistan.
Muhammad Husnain AhmadDepartment of Medicine Tentishev Satkynbai Memorial Asian Medical Institute Kant Kyrgyzstan.ORCID https://orcid.org/0009-0006-5248-0749

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psoriasis is a chronic inflammatory skin condition mediated by T-helper 1 (Th1) and T-helper 17 (Th17) cytokines, including interleukin (IL)-12, IL-23, IL-17, and tumor necrosis factor alpha (TNF-α). Ustekinumab, a human monoclonal antibody against the p40 subunit of IL-12/23, has revolutionized treatment of moderate to severe psoriasis but carries a risk of opportunistic infections due to impaired cell-mediated immunity. We describe a 54-year-old man from Kentucky with type 2 diabetes and chronic sinusitis, receiving ustekinumab for 1 year for plaque psoriasis. He presented with recurrent pneumonia unresponsive to multiple courses of amoxicillin-clavulanate, azithromycin, and levofloxacin. Chest imaging consistently demonstrated left lower lobe airspace opacities, initially attributed to nonresolving bacterial pneumonia or possible malignancy. On bronchoscopy with bronchoalveolar lavage, scattered broad-based budding yeast were visualized, and culture confirmed

Indexed as

blastomycosisbronchoalveolar lavageendemic mycosisimmunosuppressionopportunistic infectionpsoriasisustekinumab

Identifiers

PMID41040820
PMCPMC12485289

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.