ArticleCureus2025
Association Between Gut-Brain Axis Dysfunction and Vestibular Migraine Severity.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVestibular migraine (VM) is a condition characterized by regular attacks of vertigo and imbalance, along with migraine symptoms or signs. However, the role of the gut-brain axis (GBA) in mediating the severity of VM symptoms, particularly in the Pakistani population, remains poorly understood. This study aims to elucidate the relationship between GBA dysfunction and the severity of VM. METHODOLOGY: This cross-sectional study was conducted from May 2024 to April 2025 at Jinnah Hospital, Lahore, in collaboration with the Neurology and ENT departments. Convenience sampling was employed to recruit 386 participants diagnosed with VM. Data were collected using three primary instruments: the Gastrointestinal Symptom Rating Scale (GSRS), the Migraine Disability Assessment Test (MIDAS), and the Vertigo Symptom Scale-Short Form (VSS-SF). Demographic and lifestyle data were also collected. Pearson correlation, independent t-tests, analysis of variance (ANOVA), and multiple linear regression were used to study the correlation between GBA dysfunction and VM severity.
resultsThe sample included 386 participants, with males (296, 77%) and participants aged 60 years or older (154, 40%). Positive correlations were significant between gastrointestinal symptoms, migraine-related disability, and the severity of vertigo (
conclusionsThe study demonstrates an association between GBA-related symptoms and greater VM severity. These findings highlight the potential importance of assessing gastrointestinal and psychological comorbidities in the management of VM, particularly in Pakistani clinical settings where such factors may be overlooked. Future research should investigate the therapeutic potential of gut-targeted interventions using longitudinal designs and objective measures to clarify causal relationships and assess efficacy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.