Evidence map›Paper›PMID 41040603›Full record

ArticleJournal of dental sciences2025

A novel buccal bone augmentation technique around non-contained and exposed implant threads: Clinical, histologic and histomorphometric evaluations on the treatment outcome.

Myron Nevins, Dong-Wook Chang, Stefano Parma-Benfenati, Primo Galletti, Chia-Yu Jennifer Chen, Miruna Maracine, Traian Comanescu, Wei-Jen Chang, David M Kim

Abstract read
In one paragraph

Article in Journal of dental sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Myron NevinsDepartment of Oral Medicine, Infection and Immunity, Division of Periodontology, Harvard School of Dental Medicine, Boston, MA, USA.
Dong-Wook ChangClinical Associate Professor of Kyunghee University School of Dentistry, Dental Hospital, Republic of Korea.
Stefano Parma-BenfenatiDepartment of Surgical Sciences, Section of Periodontology, University of Turin, Turin, Italy.
Primo GallettiDepartment of Translational Medicine, School of Dentistry, University of Ferrara, Ferrara, Italy.
Chia-Yu Jennifer ChenDepartment of Oral Medicine, Infection and Immunity, Division of Periodontology, Harvard School of Dental Medicine, Boston, MA, USA.
Miruna MaracinePrivate Practice (Dentalevo Clinic), Bucharest, Romania.
Traian ComanescuPrivate Practice (ARRA Dental Clinique), Bucharest, Romania.
Wei-Jen ChangSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan.
David M KimDepartment of Oral Medicine, Infection and Immunity, Division of Periodontology, Harvard School of Dental Medicine, Boston, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/purpose: Buccal dehiscence defects around dental implants pose a significant clinical challenge, particularly when minimal residual bone remains. This prospective study aimed to evaluate a novel two-layer bovine-derived grafting approach-a moldable paste-type material layered with particulate bone-protected by a collagen membrane to encourage new bone formation on exposed implant threads. Materials and methods: Three partially or fully edentulous patients requiring implant-supported rehabilitation were enrolled. A total of 17 implants were placed; among these, three "study implants" exhibited pronounced buccal bone dehiscences and were grafted with the investigated protocol. Six months postoperatively, the designated study implants were retrieved en bloc and processed for histologic and histomorphometric analyses. Bone-to-implant contact (BIC) was measured on both buccal and lingual aspects to assess new bone formation on previously exposed implant threads. Results: All implant sites healed uneventfully, without complications such as wound dehiscence or infection. Histology showed newly formed mineralized tissue in direct contact with the implant surface, supported by a mean total BIC of 67.32 ± 6.27 %. The mean buccal BIC was 66.56 ± 5.52 %, suggesting that some degree of new bone formation occurred in the areas of original thread exposure, although residual graft particles were frequently noted. Conclusion: Within the limits of this preliminary study, the findings suggest that the combined bovine-derived paste and particulate graft technique may help regenerate buccal bone and facilitate osseointegration on exposed implant threads. Further investigations with larger patient samples and extended observation periods are needed to corroborate and refine these encouraging early results.

Indexed as

Alveolar bone lossAlveolar ridge augmentationBone substitutesDental implantsHistologyHumans

Identifiers

PMID41040603
PMCPMC12485454

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.