ArticleJournal of dental sciences2025
Artificial intelligence-assisted enhancement of diagnostic accuracy and efficiency in detecting cervical lymph node metastases in oral squamous cell carcinoma.
Article in Journal of dental sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background/purpose: Cervical lymph node metastasis represents a critical prognostic factor in oral squamous cell carcinoma (SCC); however, early-stage or subtle metastases often pose diagnostic challenges under conventional microscopy. Recent advancements in artificial intelligence (AI) offer promising solutions to enhance diagnostic accuracy and efficiency. This study aimed to evaluate the extent to which AI-assisted tools can improve diagnostic performance and efficiency in the detection of cervical lymph node metastases. Materials and methods: Sixty-six hematoxylin-eosin-stained slides containing 621 lymph nodes from oral SCC cases were digitized. Four participants (two oral pathologists, one postgraduate year (PGY) resident, one fourth-year dental student) reviewed slides with and without the AI-assistant tool. Diagnostic accuracy and interpretation time were compared. Results: AI assistance significantly improved diagnostic accuracy and efficiency across different participants. False positives and false negatives decreased notably, especially for junior participants. Review time was also significantly shortened for negative and macrometastatic slides ( Conclusion: The AI-assisted tool improved diagnostic accuracy and efficiency in detecting cervical lymph node metastases in oral SCC. It may serve as a preliminary screening tool and a valuable educational aid for training junior pathologists, underscoring its potential for broader application in digital pathology.
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