ArticleJournal of dental sciences2025
Anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody positivity in oral lichen planus patients with macrocytosis.
Article in Journal of dental sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Higher serum gastric parietal cell antibody titers are associated with increased frequencies of macrocytosis, vitamin B12 deficiency, and hyperhomocysteinemia in patients with oral lichen planus.Journal of dental sciences · 2026Article
- Gastric parietal cell and thyroid autoantibodies in patients with oral lichen planus.Journal of dental sciences · 2026Article
- The presence of thyroid autoantibodies is not associated with anemia, hematinic deficiencies, and hyperhomocysteinemia in oral lichen planus patients.Journal of dental sciences · 2026Article
- Prevalences of vitamin B12 deficiency, pernicious anemia, macrocytosis, and hyperhomocysteinemia in 532 serum gastric parietal cell antibody-positive oral mucosal disease patients.Journal of dental sciences · 2026Article
- Anemia, hematinic deficiencies, and hyperhomocysteinemia in younger and older oral lichen planus patients.Journal of dental sciences · 2026Article
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Authors and funding
6 authors.
Funding
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Abstract
Background/purpose: Macrocytosis is defined as having the mean corpuscular volume (MCV) ≥ 100 fL. This study evaluated whether 36 oral lichen planus (OLP) patients with macrocytosis (macrocytosis/OLP patients) had significantly higher frequencies of anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody (GPCA) positivity than 588 healthy control subjects or 588 OLP patients. Materials and methods: Complete blood count, serum iron, vitamin B12, folic acid, homocysteine, and GPCA levels in 36 macrocytosis/OLP patients, 588 OLP patients, and 588 healthy control subjects were measured and compared. Results: We found that 66.7 %, 8.3 %, 91.7 %, 0.0 %, 94.4 %, and 80.6 % of 36 macrocytosis/OLP patients were diagnosed as having blood hemoglobin and serum iron, vitamin B12, and folic acid deficiencies, hyperhomocysteinemia, and serum GPCA positivity, respectively. Moreover, 36 macrocytosis/OLP patients had significantly higher frequencies of blood hemoglobin and serum vitamin B12 deficiencies, hyperhomocysteinemia, and serum GPCA positivity than 588 healthy control subjects or 588 OLP patients (all Conclusion: There are significantly higher frequencies of anemia and serum iron and vitamin B12 deficiencies, hyperhomocysteinemia, and serum GPCA positivity in 36 macrocytosis/OLP patients than in 588 healthy control subjects. Moreover, 36 macrocytosis/OLP patients also have significantly higher frequencies of anemia, serum vitamin B12 deficiency, hyperhomocysteinemia, and serum GPCA positivity than 588 OLP patients.
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