ReviewFrontiers in oncology2025
3D-printed biopolymer-based microneedle for enhanced photodynamic therapy in melanoma treatment.
Review in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Photodynamic Therapy for Keratinocytic Precancerous Lesions and Non-Melanoma Skin Cancer: A Narrative Review.International journal of molecular sciences · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Melanoma is a highly aggressive cancer with poor prognosis and resistance to many treatments, especially after metastasis. Developing new preventive and adjuvant therapies is critical for improving melanoma outcomes. Photodynamic therapy (PDT) has shown potential in selectively targeting malignant cells while minimizing damage to healthy tissue. However, improving the delivery of photosensitizers (PS) to melanoma cells while reducing systemic toxicity remains a challenge. Microneedles, a transcutaneous drug delivery method, offer advantages such as better patient compliance and easier management compared to traditional methods like intramuscular or intravenous injection. Despite these benefits, manufacturing precise microneedles remains a hurdle. Recent research has focused on 3D printing techniques for creating transdermal drug delivery devices, including microneedles. This review summarizes recent advantages in 3D printed biopolymer-based drug delivery systems using microneedles, evaluates their potential, and discusses the challenges and future prospects of 3D printing in transdermal therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.