Evidence map›Paper›PMID 41040475›Full record

ArticleFrontiers in sports and active living2025

Effects of tDCS combined with TENS in relieving pain and improving gait patterns during stepping over obstacles among older adults with knee osteoarthritis.

Xinmeng Zhang, Dongmei Wang, Qingqing Song, Xin Luo, Yubin Ge, Peixin Shen, Qipeng Song

Abstract read
In one paragraph

Article in Frontiers in sports and active living, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xinmeng ZhangGraduate School, Shandong Sport University, Jinan, China.
Dongmei WangBiomechanics Laboratory College of Human Movement Science, Beijing Sport University, Beijing, China.
Qingqing SongGraduate School, Shandong Sport University, Jinan, China.
Xin LuoGraduate School, Shandong Sport University, Jinan, China.
Yubin GeGraduate School, Shandong Sport University, Jinan, China.
Peixin ShenCollege of Sports and Health, Shandong Sport University, Jinan, China.
Qipeng SongCollege of Sports and Health, Shandong Sport University, Jinan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Older adults with knee osteoarthritis (KOA) exhibit an elevated risk of falls during obstacle negotiation, primarily due to pain-induced gait deviations. While transcutaneous electrical nerve stimulation (TENS) offers modest pain relief and limited gait modulation, combining it with transcranial direct current stimulation (tDCS) may enhance the effects. This study evaluated the comparative efficacy of tDCS + TENS vs. TENS alone in mitigating pain and optimizing gait patterns during obstacle crossing in older adults with KOA. Methods: Twenty-three participants with KOA (mean age: 67.6 ± 5.0 years; BMI: 25.9 ± 2.4 kg/m Results: Statistically significant group-by-time interactions were observed for pain ( Conclusion: The combination of tDCS and TENS significantly outperformed TENS-only in reducing pain and enhancing gait adaptability during obstacle negotiation in older adults with KOA. These findings support the integration of tDCS as an adjunctive neuromodulatory strategy to amplify the therapeutic benefits of TENS in this population.

Indexed as

knee painobstacle crossingosteoarthritistranscranial direct current stimulationtranscutaneous electrical nerve stimulation

Identifiers

PMID41040475
PMCPMC12484165

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.