Evidence map›Paper›PMID 41040427›Full record

ReviewJournal of multidisciplinary healthcare2025

The Current Situation and Future Trends of Ergothioneine in Biology and Medical Research: A Bibliometric Analysis.

Yixian Fu, Haiying Guan, Mingna Yu, Ping Jiang, Xiaojun He, Jidan Bao, Binjie Zhang, Yan Li

Abstract readReview
In one paragraph

Review in Journal of multidisciplinary healthcare, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yixian FuDepartment of Clinical Nutrition, Zhoushan Hospital, Zhoushan, Zhejiang, People's Republic of China.
Haiying GuanDepartment of Basic Medicine, Shangrao Health Vocational College, Shangrao, Jiangxi, People's Republic of China.
Mingna YuDepartment of Clinical Nutrition, Zhoushan Hospital, Zhoushan, Zhejiang, People's Republic of China.
Ping JiangDepartment of Clinical Nutrition, Zhoushan Hospital, Zhoushan, Zhejiang, People's Republic of China.
Xiaojun HeDepartment of Clinical Nutrition, Zhoushan Hospital, Zhoushan, Zhejiang, People's Republic of China.
Jidan BaoDepartment of Clinical Nutrition, Zhoushan Hospital, Zhoushan, Zhejiang, People's Republic of China.
Binjie ZhangDepartment of Cardiothoracic Surgery, Zhoushan Hospital, Zhoushan, Zhejiang, People's Republic of China.
Yan LiDepartment of Clinical Nutrition, Zhoushan Hospital, Zhoushan, Zhejiang, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Ergothioneine (EGT) is a natural antioxidant with multiple cellular protective properties. Recently, due to the improvement of production efficiency, EGT-related products have been more widely used. This paper studies the present situation of global research trends and hotspots of EGT to better grasp the direction of EGT research in biology and medical. Methods: We searched for relevant literature on EGT in the Web of Science Core Collection (WOSCC) and SciFinder databases on August 16, 2025. CiteSpace, VOSviewer, Tableau Desktop, Microsoft Excel, Bibliometrix program package and Biorender software are used for statistical analysis and visualisation. Results: A total of 800 articles were collected. It is found that the average growth rate of EGT's publications in biology and medicine from 1996 to 2025 was 17.33%. Based on the statistical results by country/region, it is evident that the primary focal areas of research activity within this domain exhibit concentrated distribution across the Americas, Asia, and Europe. Among the top ten authors in terms of publication volume, six are from Asia, three are from Poland in Europe, and one is from the United States (USA) in the Americas. The highest H-index ranking author is Halliwell B (169). Conclusion: Based on the keyword visualisation results, the current research hotspots are mainly divided into three clusters: 1) The absorption, distribution, anti-inflammatory and antioxidant biological molecular mechanisms of EGT in vivo. 2) The impact of EGT's antioxidant and anti-inflammatory effects on various diseases; 3) The source of EGT, the antioxidant potential of edible fungi in vitro, and its influencing factors. At present, research on EGT in biology and medicine mainly focuses on basic theories, so we believe that clinical trial research will become a hot trend in the future.

Indexed as

bibliometric analysisergothioneinefungihealthmushroom

Identifiers

PMID41040427
PMCPMC12484114

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.