Evidence map›Paper›PMID 41040362›Full record

ArticlebioRxiv : the preprint server for biology2025

Dissecting Gene Regulatory Networks Governing Human Cortical Cell Fate.

Jingwen W Ding, Chang N Kim, Megan S Ostrowski, Yashodara Abeykoon, Bryan J Pavlovic, Jenelle L Wallace, Tomasz J Nowakowski, Alex A Pollen

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Jingwen W DingThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.ORCID 0009-0009-6306-1437
Chang N KimDepartment of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0001-7921-4447
Megan S OstrowskiThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0001-9845-9319
Yashodara AbeykoonThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0002-0900-138X
Bryan J PavlovicThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0002-7751-5315
Jenelle L WallaceThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0002-9565-2751
Tomasz J NowakowskiThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0003-2345-4964
Alex A PollenThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0003-3263-8634

Funding

A Multidisciplinary Center for Developing Human and Non-human Primate Brain Cell AtlasesUM1MH130991 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Hao Huang, ARNOLD KRIEGSTEIN · 2022 to 2026
$25.2M
Discovering human divergent activity-regulated elements using comparative, computational, and functional approachesR01MH134981 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KATHERINE S. POLLARD, ALEXANDER A POLLEN · 2023 to 2026
$3.3M
Establishing A Stem Cell Biology Platform for Decoding the Genetic Basis of Human Brain SpecializationsDP2MH122400 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI POLLEN, ALEXANDER A · 2019 to 2019
$2.4M
Developmental Timing During Cortical DevelopmentR01NS123263 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Tomasz Nowakowski · 2022 to 2026
$2.1M
Illumina NovaSeq 6000 Sequencing SystemS10OD028511 · OD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHOW, ERIC D · 2020 to 2020
$583k
BD FACSAria II Flow CytometerS10RR028962 · NCRR · J. DAVID GLADSTONE INSTITUTES · PI CAVROIS, MARIELLE · 2011 to 2011
$544k
NCRR NIH HHS S10 RR028962NIH HHS S10 OD028511NIMH NIH HHS DP2 MH122400NIMH NIH HHS R01 MH134981NIMH NIH HHS UM1 MH130991NINDS NIH HHS R01 NS123263
6 · The paper itself

Abstract

Human cortical neurogenesis involves conserved and specialized developmental processes during a restricted window of prenatal development. Radial glia (RG) neural stem cells shape cortical cell diversity by giving rise to excitatory neurons, oligodendrocytes, and astrocytes, as well as olfactory bulb interneurons (INs) and a recently characterized population of cortical INs

Identifiers

PMID41040362
PMCPMC12485932

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.