Evidence map›Paper›PMID 41040355›Full record

ArticlebioRxiv : the preprint server for biology2025

Targeting RAD52 overcomes PARP inhibitor resistance in preclinical

Yukihide Ota, Vijayalaxmi Gupta, Bisiayo E Fashemi, Moreniola Akande, Preedia Babu, Prasanth Thuthika, Maia L Elizagaray, Lulu Sun, Brooke Sanders, Lindsay M Kuroki and 12 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Yukihide OtaDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center. St Louis, MO, USA.ORCID 0000-0002-5167-1918
Vijayalaxmi GuptaDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center. St Louis, MO, USA.ORCID 0000-0001-8915-3393
Bisiayo E FashemiDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center. St Louis, MO, USA.ORCID 0000-0002-1872-8011
Moreniola AkandeDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center. St Louis, MO, USA.
Preedia BabuDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center. St Louis, MO, USA.ORCID 0000-0002-0305-0412
Prasanth ThuthikaDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center. St Louis, MO, USA.
Maia L ElizagarayDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center. St Louis, MO, USA.ORCID 0000-0002-4570-172X
Lulu SunDivision of Anatomic and Molecular Pathology, Department of Pathology and Immunology, Washington University School of Medicine. St Louis, MO, USA.
Brooke SandersDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center. St Louis, MO, USA.
Lindsay M KurokiDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center. St Louis, MO, USA.ORCID 0000-0002-2141-7310
Carolyn K McCourtDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center. St Louis, MO, USA.ORCID 0000-0003-2229-8971
Andrea R HagemannDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center. St Louis, MO, USA.ORCID 0000-0002-3484-0046
Ian S HagemannDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center. St Louis, MO, USA.ORCID 0000-0002-3855-9745
Premal H ThakerDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center. St Louis, MO, USA.
David G MutchDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center. St Louis, MO, USA.
Matthew A PowellDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center. St Louis, MO, USA.
Krzysztof HyrcDepartment of Neurology, Washington University School of Medicine. St Louis, MO, St Louis, MO, USA.
Priyanka VermaDivision of Oncology, Department of Medicine, Washington University School of Medicine. St Louis, MO, and Alvin J. Siteman Cancer Center. St Louis, MO, USA.
John KraisDivision of Oncology, Department of Medicine, Washington University School of Medicine. St Louis, MO, and Alvin J. Siteman Cancer Center. St Louis, MO, USA.ORCID 0000-0002-3916-3435
Benjamin G BitlerDivision of Reproductive Sciences, University of Colorado, Aurora, CO, USA.ORCID 0000-0002-5809-5271
Mary MullenDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center. St Louis, MO, USA.
Dineo KhabeleDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center. St Louis, MO, USA.ORCID 0000-0002-5151-5210

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0M
Epigenetic Drug Regimens for Homologous Recombination Proficient Ovarian Cancer - Diversity SupplementR01CA243511 · NCI · WASHINGTON UNIVERSITY · PI KHABELE, DINEO · 2020 to 2024
$2.5M
Whole slide scanner for translational neuroscience researchS10OD032121 · OD · WASHINGTON UNIVERSITY · PI WONG, MICHAEL · 2023 to 2023
$430k
Targeting Cyclin E in Ovarian Cancer with Histone Deacetylase InhibitorsR21CA210210 · NCI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI KHABELE, DINEO · 2017 to 2018
$384k
NCI NIH HHS P30 CA091842NCI NIH HHS R01 CA243511NCI NIH HHS R21 CA210210NIH HHS S10 OD032121
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41040355
PMCPMC12485677

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.