Evidence map›Paper›PMID 41040327›Full record

ArticlebioRxiv : the preprint server for biology2025

Comparison of Human Melanoma Single Cell Profiles to Evolutionary Medicine Model

Yanting Xing, Rachel Carrol, X Maggs, Wes C Warren, Manfred Schartl, Yuan Lu

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Yanting Xing
Rachel Carrol
X Maggs
Wes C Warren
Manfred Schartl
Yuan Lu

Funding

Advancement of the Xiphophorus Model for Studying DiseaseR24OD031467 · OD · TEXAS STATE UNIVERSITY · PI Yuan Lu, Manfred Schartl · 2022 to 2026
$3.8M
Identification and Characterization of a Endogenous EGFR Regulatory Locus in Xiphophorus GenomeR15CA223964 · NCI · TEXAS STATE UNIVERSITY · PI LU, YUAN · 2018 to 2021
$887k
NCI NIH HHS R15 CA223964NIH HHS R24 OD031467
6 · The paper itself

Abstract

Melanoma remains one of the deadliest forms of cancer. Despite recent therapeutic advances including immune checkpoint inhibitors and small-molecule kinase inhibitors, patients frequently develop treatment resistance. Novel models are needed to devise strategies that overcome resistance and further reduce melanoma-related mortality. Interspecies hybrid fish from the Xiphophorus lineage develop mutant

Identifiers

PMID41040327
PMCPMC12485733

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.