Evidence map›Paper›PMID 41040259›Full record

ArticlebioRxiv : the preprint server for biology2025

Emergence of Functional Heart-Brain Circuits in a Vertebrate.

L Hernandez-Nunez, J Avrami, S Shi, A Markarian, J Boulanger-Weill, A Zarghani-Shiraz, M Ahrens, F Engert, M C Fishman

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

L Hernandez-NunezDepartment of Molecular and Cellular Biology and Center for Brain Science, Harvard University.ORCID 0000-0003-3102-9036
J AvramiDepartment of Molecular and Cellular Biology and Center for Brain Science, Harvard University.
S ShiDepartment of Molecular and Cellular Biology and Center for Brain Science, Harvard University.
A MarkarianDepartment of Molecular and Cellular Biology and Center for Brain Science, Harvard University.
J Boulanger-WeillSorbonne Université, INSERM, CNRS, Institut de la Vision, F-75012 Paris, France.ORCID 0000-0002-1580-0778
A Zarghani-ShirazDepartment of Stem Cell and Regenerative Biology, Harvard University.
M AhrensHoward Hughes Medical Institute, Janelia Farm Research Campus.
F EngertDepartment of Molecular and Cellular Biology and Center for Brain Science, Harvard University.
M C FishmanDepartment of Stem Cell and Regenerative Biology, Harvard University.

Funding

Zooming into the fish's brain-What is really going on! Connectomics analysis of larval zebrafish.U19NS104653 · NINDS · HARVARD UNIVERSITY · PI MARK C FISHMAN · 2017 to 2026
$39.4M
Genetic and neural mechanisms underlying emerging social behavior in zebrafishR01NS124017 · NINDS · HARVARD UNIVERSITY · PI ENGERT, FLORIAN, FISHMAN, MARK C · 2024 to 2025
$1.5M
Viscerosensory Modulation of Brain Circuits in Larval ZebrafishR34NS138096 · NINDS · STANFORD UNIVERSITY · PI HERNANDEZ NUNEZ, LUIS ALONSO · 2024 to 2025
$674k
NINDS NIH HHS R01 NS124017NINDS NIH HHS R34 NS138096NINDS NIH HHS U19 NS104653
6 · The paper itself

Abstract

The early formation of sensorimotor circuits is essential for survival. While the development and function of exteroceptive circuits and their associated motor pathways are well characterized, far less is known about the circuits that convey viscerosensory inputs to the brain and transmit visceromotor commands from the central nervous system to internal organs. Technical limitations, such as the

Identifiers

PMID41040259
PMCPMC12485852

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.