Evidence map›Paper›PMID 41040168›Full record

ArticlebioRxiv : the preprint server for biology2025

Saumya Bhagat, Khushpreet Kaur, Luke O'Connor, Chun Wang, Yongjia Li, Gaurav Swarnkar, Kunjan Khanna, James E Cassat, Deborah J Veis, Gabriel Mbalaviele

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

  • Updated by
    2026
5 · Who and what money

Authors and funding

10 authors.

Saumya BhagatDivision of Bone & Mineral Diseases, Musculoskeletal Research Center, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0001-8979-7455
Khushpreet KaurDivision of Bone & Mineral Diseases, Musculoskeletal Research Center, Washington University School of Medicine, St. Louis, MO, USA.
Luke O'ConnorDivision of Bone & Mineral Diseases, Musculoskeletal Research Center, Washington University School of Medicine, St. Louis, MO, USA.
Chun WangDivision of Bone & Mineral Diseases, Musculoskeletal Research Center, Washington University School of Medicine, St. Louis, MO, USA.
Yongjia LiDivision of Bone & Mineral Diseases, Musculoskeletal Research Center, Washington University School of Medicine, St. Louis, MO, USA.
Gaurav SwarnkarDepartment of Orthopedic Surgery and Cell Biology & Physiology, Washington University School of Medicine, St. Louis, MO, USA.
Kunjan KhannaDepartment of Orthopedic Surgery and Cell Biology & Physiology, Washington University School of Medicine, St. Louis, MO, USA.
James E CassatDepartment of Pediatrics, Division of Pediatric Infectious Disease, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Deborah J VeisDivision of Bone & Mineral Diseases, Musculoskeletal Research Center, Washington University School of Medicine, St. Louis, MO, USA.
Gabriel MbalavieleDivision of Bone & Mineral Diseases, Musculoskeletal Research Center, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0003-4660-0952

Funding

Resource Based Center for Musculoskeletal Biology and Medicine (Overall Application)P30AR074992 · NIAMS · WASHINGTON UNIVERSITY · PI MATTHEW J SILVA · 2019 to 2026
$6.8M
Differential Inflammasome Regulation in the pathogenesis of S. aureus osteomyelitisR01AI161022 · NIAID · WASHINGTON UNIVERSITY · PI CASSAT, JAMES E, MBALAVIELE, GABRIEL · 2021 to 2025
$3.4M
Molecular pathways of calcium pyrophosphate deposition diseaseR01AG077732 · NIA · MEDICAL COLLEGE OF WISCONSIN · PI Gabriel Mbalaviele, Ann K Rosenthal · 2022 to 2026
$2.4M
Role of gasdermin D in bone resorptionR01AR076758 · NIAMS · WASHINGTON UNIVERSITY · PI MBALAVIELE, GABRIEL · 2020 to 2024
$1.9M
NIAID NIH HHS R01 AI161022NIAMS NIH HHS P30 AR074992NIAMS NIH HHS R01 AR076758NIA NIH HHS R01 AG077732
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

bone marrow-derived macrophagescaspase-1gasdermin Dhost-pathogen interactionIL-1βimmune evasionNLRP3 inflammasomepyroptosisStaphylococcus aureus

Identifiers

PMID41040168
PMCPMC12485927

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.