Evidence map›Paper›PMID 41040069›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2025

A local outbreak of iatrogenic botulism associated with cosmetic injections of botulinum neurotoxin-containing products, England, 2025.

Joseph Jasperse, Kate Wilson, Sana Akbar, Iain Hayden, Qudsia Naseem, Alison Worthington, Amii Coglan, Matt Hewson, Alan Young, Min Fang and 5 more

Abstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Joseph JasperseField Service North East and Yorkshire and Humber, UK Health Security Agency, Newcastle upon Tyne, United Kingdom.
Kate WilsonField Service North East and Yorkshire and Humber, UK Health Security Agency, Newcastle upon Tyne, United Kingdom.
Sana AkbarCounty Durham and Darlington NHS Foundation Trust, Durham, United Kingdom.
Iain HaydenGastrointestinal Infections, Food Safety and One Health Division, UK Health Security Agency, London, United Kingdom.
Qudsia NaseemCounty Durham and Darlington NHS Foundation Trust, Durham, United Kingdom.
Alison WorthingtonDurham County Council, Durham, United Kingdom.
Amii CoglanDurham County Council, Durham, United Kingdom.
Matt HewsonCriminal Enforcement Unit, Medicines and Healthcare products Regulatory Agency, London, United Kingdom.
Alan YoungCriminal Enforcement Unit, Medicines and Healthcare products Regulatory Agency, London, United Kingdom.
Min FangMolecular Analysis, Analytical and Biological Sciences, Science and Research, Medicines and Healthcare products Regulatory Agency, South Mimms, United Kingdom.
Yvonne LiuBacterial Vaccine Standards, Standards Lifecycle, Science and Research, Medicines and Healthcare products Regulatory Agency, South Mimms, United Kingdom.
Joanne DarkeNorth East Health Protection Team, UK Health Security Agency, Newcastle upon Tyne, United Kingdom.
Vanessa WongGastrointestinal Infections, Food Safety and One Health Division, UK Health Security Agency, London, United Kingdom.
Gauri GodboleGastrointestinal Infections, Food Safety and One Health Division, UK Health Security Agency, London, United Kingdom.
Gareth J HughesField Service North East and Yorkshire and Humber, UK Health Security Agency, Newcastle upon Tyne, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In June 2025, 25 botulism cases were identified among recipients of botulinum neurotoxin-containing cosmetic injections in North East England. A case-control study indicated that cases were more likely to have attended two specific practitioners and received an unlicensed product (p < 0.001). Testing of seized product detected a potency (370 units/vial) that was higher than listed on its labelling (200 units/vial). Strengthened regulation of cosmetic procedures is necessary for mitigating public health risks, which are exacerbated by the availability of unlicensed products.

Indexed as

Botulinum ToxinsBotulinum Toxins, Type ABotulismCosmeticsDisease OutbreaksIatrogenic DiseaseAdultAgedCase-Control StudiesEnglandFemaleHumansInjectionsMaleMiddle AgedYoung AdultBotulinum ToxinsBotulinum Toxins, Type ACosmeticsbotulinum neurotoxinBotulismClostridium botulinumEuropeiatrogenicoutbreak

Identifiers

PMID41040069
PMCPMC12495379

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.