Evidence map›Paper›PMID 41040063›Full record

ReviewEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2025

A review of childhood rotavirus vaccination policies and a presentation of vaccine coverage trends at national and regional level, Italy, 2016 to 2023.

Sara Farina, Alessandra Maio, Andrea Zaino, Luigi Russo, Walter Ricciardi, Roberto Ieraci, Leonardo Villani

Abstract readReview
In one paragraph

Review in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sara FarinaSection of Hygiene, University Department of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy.
Alessandra MaioSection of Hygiene, University Department of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy.
Andrea ZainoSection of Hygiene, University Department of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy.
Luigi RussoSection of Hygiene, University Department of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy.
Walter RicciardiSection of Hygiene, University Department of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy.
Roberto IeraciRegione Lazio - Strategie Vaccinali, Rome, Italy.
Leonardo VillaniSection of Hygiene, University Department of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUNDRotavirus is a main gastroenteritis cause in children ≤ 5 years old. In 2017, when few Italian regions had rotavirus vaccination programmes, rotavirus vaccines were included in the National Plan for Preventive Vaccination (PNPV). Although all Italian regions follow the PNPV, they each decide how to implement it, contributing to rotavirus vaccination coverage differences across the country.AIMThe objective was to assess rotavirus vaccination national/regional policies in Italy and, between 2016 and 2023, vaccination coverage trends at national and regional level.METHODSScientific and grey literature was systematically reviewed for reports on Italian national/regional policies or programmes concerning rotavirus vaccination. Their key features and strategies to increase vaccination coverage were recorded. Vaccination coverage data originating from the Ministry of Health, were analysed descriptively, or with linear regression, for national and regional trends.RESULTSAmong 418 policy/programme reports identified, 25 were included. Between 2013 and 2015, Sicilia, Calabria and Puglia had already initiated universal vaccination programmes. The PNPV 2017-19 standardised regions' offer of rotavirus vaccination. Between 2016 and 2023, vaccination coverage in Italy significantly increased (p = 0.0005) from 10.5% to 70.76%, with a 140% rise in 2019-20. Regional coverage disparities existed. Throughout 2016-23, most central Italian regions had annual coverages below national values. Bolzano annual coverage was consistently < 50%, while in Veneto, coverage reached 85.10% in 2021. In 2023, five regions had > 80% coverage.CONCLUSIONSWhile rotavirus vaccination coverage improved in Italy in 2016-23, regional disparities persist. Addressing these requires overcoming logistical and societal challenges, as well as harmonised policies.

Indexed as

GastroenteritisHealth PolicyImmunization ProgramsRotavirusRotavirus InfectionsRotavirus VaccinesVaccinationVaccination CoverageChild, PreschoolHumansInfantItalyRotavirus Vaccineshealth policyimmunizationItalys: rotavirusvaccination coverage

Identifiers

PMID41040063
PMCPMC12495378

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.