Evidence map›Paper›PMID 41039995›Full record

ReviewChembiochem : a European journal of chemical biology2025

Advances and Challenges in Bioprocess Optimization for the Synthesis of Sugar Nucleotides.

Tom L Roberts, Sebastian C Cosgrove, Gavin J Miller

Abstract readReview
In one paragraph

Review in Chembiochem : a European journal of chemical biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Advances and Challenges in Bioprocess Optimization for the Synthesis of Sugar Nucleotides.Chembiochem : a European journal of chemical biology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tom L RobertsCentre for Glycoscience and School of Chemical and Physical Sciences, Keele University, Keele, Staffordshire, ST5 5BG, UK.
Sebastian C CosgroveCentre for Glycoscience and School of Chemical and Physical Sciences, Keele University, Keele, Staffordshire, ST5 5BG, UK.
Gavin J MillerCentre for Glycoscience and School of Chemical and Physical Sciences, Keele University, Keele, Staffordshire, ST5 5BG, UK.ORCID https://orcid.org/0000-0001-6533-3306

Funding

UK Research and Innovation MR/T019522/1
6 · The paper itself

Abstract

Sugar nucleotides represent the cornerstone building blocks for glycan biosynthesis. While methods to access these crucial biomolecules using traditional batch synthetic chemistry and enzymatic approaches have blossomed, uptake using flow-based synthesis is burgeoning. This perspective analyzes recent advances concerning enzyme immobilization and continuous flow biocatalysis for sugar nucleotide production and usage. Evaluation of related technologies is also discussed, highlighting new enzyme immobilization approaches, novel reactor design, and improved downstream processing as areas that must evolve to enable wider, scalable access to sugar nucleotides as commodity chemicals.

Indexed as

NucleotidesSugarsBiocatalysisEnzymes, ImmobilizedEnzymes, ImmobilizedNucleotidesSugarsbiocatalysisbioprocessglycanimmobilisationsugar nucleotide

Identifiers

PMID41039995
PMCPMC12582152

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.