Evidence map›Paper›PMID 41039658›Full record

ArticlePhotochemistry and photobiology

Far-infrared irradiation attenuates platelet-derived growth factor-stimulated vascular smooth muscle cell migration through protein phosphatase 2A-mediated Akt inhibition.

Na-Young Lee, Seo-Hyeon Kim, Young Jin Kang, Il-Kug Kim, Yun-Jin Hwang, Du-Hyong Cho

Abstract read
In one paragraph

Article in Photochemistry and photobiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Na-Young LeeDepartment of Pharmacology, College of Medicine, Yeungnam University, Daegu, South Korea.
Seo-Hyeon KimDepartment of Pharmacology, College of Medicine, Yeungnam University, Daegu, South Korea.
Young Jin KangDepartment of Pharmacology, College of Medicine, Yeungnam University, Daegu, South Korea.
Il-Kug KimDepartment of Plastic and Reconstructive Surgery, College of Medicine, Yeungnam University, Daegu, South Korea.
Yun-Jin HwangDepartment of Pharmacology, College of Medicine, Yeungnam University, Daegu, South Korea.
Du-Hyong ChoDepartment of Pharmacology, College of Medicine, Yeungnam University, Daegu, South Korea.ORCID https://orcid.org/0000-0002-9891-1464

Funding

National Research Foundation of Korea 2022R1A5A2018865National Research Foundation of Korea 2022R1F1A1069879
6 · The paper itself

Abstract

Vascular smooth muscle cell (VSMC) migration is a crucial factor contributing to the development and progression of atherosclerosis and in-stent restenosis. Although far-infrared (FIR) rays have been suggested to alleviate atherosclerosis, their effects on VSMC migration remain unclear. To investigate the underlying mechanisms, we performed wound healing migration assays, cell viability assays, transfection with wild-type (WT)-Akt gene, western blot analyses, and ex vivo studies using isolated rat aortas. FIR irradiation inhibited basal and platelet-derived growth factor (PDGF)-stimulated VSMC migration without affecting cell viability, and decreased the phosphorylation of Akt at Ser473 (p-Akt-Ser

Indexed as

Cell MovementInfrared RaysMuscle, Smooth, VascularMyocytes, Smooth MusclePlatelet-Derived Growth FactorProtein Phosphatase 2Proto-Oncogene Proteins c-aktAnimalsCells, CulturedMalePhosphorylationRatsRats, Sprague-DawleyPlatelet-Derived Growth FactorProtein Phosphatase 2Proto-Oncogene Proteins c-aktAktatherosclerosisfar‐infraredmigrationprotein phosphatase 2Avascular smooth muscle cells

Identifiers

PMID41039658
PMCPMC13383185

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.