Evidence map›Paper›PMID 41039606›Full record

ArticleCell communication and signaling : CCS2025

Investigation of the heterogeneity of cancer cells using single cell Ca

Amélie E Bura, Camille Caussette, Maxime Guéguinou, Dorine Bellanger, Alison Robert, Mathilde Cancel, Margot Lacouette-Rata, Gaëlle Fromont, Christophe Vandier, Karine Mahéo and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell communication and signaling : CCS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Amélie E Bura *Inserm UMR1069 Niche Nutrition Cancer and Oxydative Metabolism (N2COx), University of Tours, Tours, France.
Camille Caussette *Inserm UMR1069 Niche Nutrition Cancer and Oxydative Metabolism (N2COx), University of Tours, Tours, France.
Maxime GuéguinouInserm UMR1069 Niche Nutrition Cancer and Oxydative Metabolism (N2COx), University of Tours, Tours, France.
Dorine BellangerInserm UMR1069 Niche Nutrition Cancer and Oxydative Metabolism (N2COx), University of Tours, Tours, France.
Alison RobertInserm UMR1069 Niche Nutrition Cancer and Oxydative Metabolism (N2COx), University of Tours, Tours, France.
Mathilde CancelInserm UMR1069 Niche Nutrition Cancer and Oxydative Metabolism (N2COx), University of Tours, Tours, France.
Margot Lacouette-RataInserm UMR1069 Niche Nutrition Cancer and Oxydative Metabolism (N2COx), University of Tours, Tours, France.
Gaëlle FromontInserm UMR1069 Niche Nutrition Cancer and Oxydative Metabolism (N2COx), University of Tours, Tours, France.
Christophe VandierInserm UMR1069 Niche Nutrition Cancer and Oxydative Metabolism (N2COx), University of Tours, Tours, France.
Karine MahéoInserm UMR1069 Niche Nutrition Cancer and Oxydative Metabolism (N2COx), University of Tours, Tours, France.
Thierry Brouard *LIFAT UR6300, University of Tours, Tours, France.
David Crottès *Inserm UMR1069 Niche Nutrition Cancer and Oxydative Metabolism (N2COx), University of Tours, Tours, France. david.crottes@univ-tours.fr.

Funding

Cancéropôle Grand Ouest IMACALSEQCAPCancéropôle Grand Ouest LNCRESISTINSERM PCSI MULTINIRRégion Centre-Val de Loire APR-IA CAMITHERAPALRégion Centre-Val de Loire APR-IR LCAPRO
6 · The paper itself

Abstract

backgroundCalcium (Ca

methodsTo characterize and investigate the heterogeneity of oncogenic Ca

resultsFrom an initial dataset of 27,439 agonist-induced Ca

conclusionsOur method demonstrates the potential of Ca

Indexed as

CalciumNeoplasmsSingle-Cell AnalysisCalcium SignalingCell Line, TumorDrug Resistance, NeoplasmHumansNeural Networks, ComputerCalciumCancer cellsColorectal cancerDocetaxel resistanceGraph-based unsupervised clusteringPredictive neural networksProstate cancerSingle cell calcium imaging

Identifiers

PMID41039606
PMCPMC12492923

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.