ArticleBMC nutrition2025
Paleolithic diet fraction and score in post hoc data analysis of a randomized controlled trial with lifestyle interventions for abdominal obesity.
Article in BMC nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01208558 (Whole Grain Versus no Grain With or Without Physiotherapy-promoted Exercise for Waist Loss), which is not on this map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Whole Grain Versus no Grain With or Without Physiotherapy-promoted Exercise for Waist Loss
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPaleolithic Diet Fraction (PDF) and Paleolithic Diet Score (PDS) are both measures of how closely a food intake conforms to a Paleolithic dietary pattern. PDF is calculated directly from an individual's absolute food intake and PDS is an aggregated score based on an individual's food intake relative to a population. Both are inversely associated with all-cause and cause-specific mortality, coronary events and cancer. Here, for the first time, both measures are calculated in the same population and compared in a post hoc data analysis of a two-year-long randomized controlled trial (RCT) examining effects of lifestyle changes on waist circumference.
methodsSeventy-three participants with increased waist circumference and at least one additional risk factor for cardiovascular disease were randomized to a diet based on current dietary guidelines with or without grains and with or without physical exercise or controls. Of these, this post hoc analysis included the 57 participants (36 women and 21 men, aged 31-79 years) who completed the study per protocol with dietary data. Mean daily PDF and PDS were calculated using four-day weighed food records at baseline, 12 months, and 24 months. Correlations between PDF and PDS, and their respective associations with cardiometabolic outcomes were examined.
resultsThe mean daily PDF for energy at baseline, 12, and 24 months was 36%, 44%, and 42%, respectively. The absolute values of PDF and PDS, and their relative changes, demonstrated moderate to strong correlations during the study (r
conclusionsThere were moderate to strong correlations between PDF and PDS and no associations between PDF or PDS and cardiometabolic outcome measures, with the latter result possibly due to only modest changes in diet and an absence of outcome effects. REGISTRY: ClinicalTrials.gov, TRN: NCT01208558, Registration date: 24 September 2010. Retrospectively registered.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.