Evidence map›Paper›PMID 41039407›Full record

SynthesisBMC medical education2025

The effectiveness of case-based learning compared with lecture-based learning in pharmacy education: a systematic review and meta-analysis.

Min Chen, Xinyao Li, Qingming Liu, Jing Zhou, Xiaofang Fan, Yantao Liu, Yunzhu Lin, Jiaqi Ni

Abstract readSystematic ReviewMeta-AnalysisComparative Study
In one paragraph

Synthesis in BMC medical education, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Min ChenDepartment of Pharmacy/Evidence-Based Pharmacy Center, West China Second University Hospital, Sichuan University, Chengdu, China.
Xinyao LiWest China School of Pharmacy, Sichuan University, Chengdu, China.
Qingming LiuWest China School of Pharmacy, Sichuan University, Chengdu, China.
Jing ZhouWest China School of Pharmacy, Sichuan University, Chengdu, China.
Xiaofang FanWest China School of Pharmacy, Sichuan University, Chengdu, China.
Yantao LiuDepartment of Pharmacy/Evidence-Based Pharmacy Center, West China Second University Hospital, Sichuan University, Chengdu, China.
Yunzhu LinDepartment of Pharmacy/Evidence-Based Pharmacy Center, West China Second University Hospital, Sichuan University, Chengdu, China.
Jiaqi NiDepartment of Pharmacy/Evidence-Based Pharmacy Center, West China Second University Hospital, Sichuan University, Chengdu, China. jiaqini007@163.com.

Funding

Fundamental Research Funds for the Central Universities YJ202339Sichuan Science and Technology Program 2025JDKP0108Sichuan University Research Funds for Graduate Education and Teaching Reform GSSCU2023120
6 · The paper itself

Abstract

backgroundCase-based learning (CBL), an innovative teaching approach distinct from traditional methodologies, has gained increasing popularity in pharmacy education. This study aims to conduct a systematic investigation into the effectiveness of CBL, offering evidence-based insights to inform future research and instructional practices in pharmacy education.

methodsA comprehensive search of related literature published prior to June 2023 was performed across seven databases, including China National Knowledge Infrastructure (CNKI), Wanfang Database, VIP China Science and Technology Journal, PubMed, Cochrane Library, Embase, and Medline. Following predefined inclusion and exclusion criteria, eligible studies underwent rigorous screening. The Cochrane Risk of Bias Assessment Tool was utilized to assess methodological quality, with RevMan 5.4.1 employed for systematic review and meta-analysis.

resultsAn initial retrieval yielded 2,267 studies, of which 11 studies involving 1,339 pharmacy students met the final inclusion criteria. Based on the studies included, the CBL group demonstrated significantly higher exam scores compared to the lecture-based learning (LBL) group (standardized mean difference [SMD] = 0.58, 95% confidence interval [CI] [0.39, 0.77], P < 0.05). In addition, CBL led to substantial enhancements in communication/collaboration skills (risk ratio [RR] = 2.49, 95% CI [1.17, 5.27], P < 0.05), problem-solving abilities (RR = 2.19, 95% CI [1.26, 3.80], P < 0.05), and clinical practice skills (RR = 2.39, 95% CI [1.46, 3.92], P < 0.05). Moreover, students reported higher satisfaction with CBL-based instruction compared to LBL (RR = 1.63, 95% CI [1.22, 2.18], P < 0.05).

conclusionsCBL effectively enhances pharmacy students' exam performance, communication and team collaboration skills, problem-solving abilities, clinical practice skills, and instructional satisfaction.

trial registrationInternational Prospective Register of Systematic Reviews (PROSPERO), CRD 42,024,537,606.

Indexed as

Education, PharmacyProblem-Based LearningEducational MeasurementHumansStudents, PharmacyCase-based learningLecture-based learningMeta-analysisPharmacy educationSystematic review

Identifiers

PMID41039407
PMCPMC12492731

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.