Evidence map›Paper›PMID 41039336›Full record

ArticleBMC pediatrics2025

Bacterial etiology and antimicrobial resistance patterns of pediatric UTIs in the West bank, Palestine: a cross-sectional study.

Tala Amleh, Aseel Salah, Reem Hamayel, Bayan A Ibrahim, Hamza Sayeh, Suha Hamshari, Mohammad Qadi

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Article in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Tala AmlehDepartment of Medicine, Faculty of Medicine and Allied Medical Sciences, An-Najah National University, P.O. Box. 7, Nablus, State of Palestine.
Aseel SalahDepartment of Medicine, Faculty of Medicine and Allied Medical Sciences, An-Najah National University, P.O. Box. 7, Nablus, State of Palestine.
Reem HamayelDepartment of Medicine, Faculty of Medicine and Allied Medical Sciences, An-Najah National University, P.O. Box. 7, Nablus, State of Palestine.
Bayan A IbrahimDepartment of Biomedical Sciences and Basic Clinical Skills, Faculty of Medicine and Allied Medical Sciences, An-Najah National University, P.O. Box. 7, Nablus, State of Palestine.
Hamza SayehDepartment of Medicine, Faculty of Medicine and Allied Medical Sciences, An-Najah National University, P.O. Box. 7, Nablus, State of Palestine.
Suha HamshariDepartment of Medicine, Faculty of Medicine and Allied Medical Sciences, An-Najah National University, P.O. Box. 7, Nablus, State of Palestine.
Mohammad QadiDepartment of Biomedical Sciences and Basic Clinical Skills, Faculty of Medicine and Allied Medical Sciences, An-Najah National University, P.O. Box. 7, Nablus, State of Palestine. m.qadi@najah.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionUrinary tract infections (UTIs) are among the most common bacterial infections in children. This study aimed to investigate the distribution of bacterial uropathogens and their antimicrobial resistance patterns among hospitalized pediatric patients with UTIs in governmental hospitals across the West Bank, Palestine. The findings are intended to support evidence-based empirical treatment strategies and inform local antimicrobial stewardship efforts.

methodsThis is a cross-sectional study, analyzed urine culture results from pediatric patients with UTI symptoms admitted to governmental hospitals across three regions of the West Bank in 2021–2022, using data from the Ministry of Health’s electronic database.

results3,949 positive urine culture results were analyzed; 58.5% of the total were aged ≥ 2 years, and 2883 were females (73%), with Gram-negative bacteria accounting for 87.1%. The most common pathogen was Escherichia coli (61.7%). The prevalence of multidrug-resistant (MDR) bacteria was 34.3%. Among Gram-negative isolates, 34.5% were MDR, 33.1% were extended-spectrum beta-lactamase (ESBL) producers, and 3.3% were carbapenem-resistant Enterobacterales (CRE). The highest MDR percentage was in Proteus spp. (50.6%) followed by Klebsiella spp. (45.4%), and E. coli (32.6%). According to matching with the empirical antibiotics, Ampicillin shows 16.8%, Ceftriaxone shows 49.5%, and Cefotaxime shows 51.9%.

conclusionOur findings highlight the high prevalence of MDR bacteria among pediatric UTI patients in the West Bank. E. coli and Klebsiella spp. were the predominant pathogens, showing considerable resistance to commonly used antibiotics. These results underscore the need to reassess empirical UTI treatment regimens, conduct routine antibiogram monitoring, and implement coordinated infection control and antibiotic stewardship programs across the West Bank, Palestine.

Indexed as

Urinary Tract InfectionsAdolescentAnti-Bacterial AgentsChildChild, PreschoolCross-Sectional StudiesDrug Resistance, BacterialDrug Resistance, Multiple, BacterialFemaleGram-Negative Bacterial InfectionsHumansInfantMaleMiddle EastAnti-Bacterial AgentsAntibiotic stewardshipAntimicrobial resistance (AMR)Healthcare sustainability in palestine.Infection prevention and controlMultidrug-resistant (MDR) pathogensPediatric infectious diseasesPublic health resilienceUrinary tract infection (UTI)

Identifiers

PMID41039336
PMCPMC12492803

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.