Evidence map›Paper›PMID 41039207›Full record

ArticleBMC cancer2025

Prognostic factors of locally advanced cervical cancer after concurrent chemoradiotherapy: a retrospective study.

Xiuying Li, Zejia Mao, Qiaoling Li, Misi He, Mingfang Guo, Hao He, Yue Huang, Qian Zheng, Ling Long, Jing Wang and 1 more

Abstract read
In one paragraph

Article in BMC cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiuying LiDepartment of Gynecologic Oncology, Chongqing University Cancer Hospital & Chongqing Cancer Institute & Chongqing Cancer Hospital, Hanyu Road No. 181, Shapingba District, Chongqing, 400030, China.
Zejia MaoSchool of Medicine, Chongqing University, Chongqing University Cancer Hospital, Chongqing, China.
Qiaoling LiDepartment of Gynecologic Oncology, Chongqing University Cancer Hospital & Chongqing Cancer Institute & Chongqing Cancer Hospital, Hanyu Road No. 181, Shapingba District, Chongqing, 400030, China.
Misi HeDepartment of Gynecologic Oncology, Chongqing University Cancer Hospital & Chongqing Cancer Institute & Chongqing Cancer Hospital, Hanyu Road No. 181, Shapingba District, Chongqing, 400030, China.
Mingfang GuoDepartment of Gynecologic Oncology, Chongqing University Cancer Hospital & Chongqing Cancer Institute & Chongqing Cancer Hospital, Hanyu Road No. 181, Shapingba District, Chongqing, 400030, China.
Hao HeDepartment of Gynecologic Oncology, Chongqing University Cancer Hospital & Chongqing Cancer Institute & Chongqing Cancer Hospital, Hanyu Road No. 181, Shapingba District, Chongqing, 400030, China.
Yue HuangDepartment of Gynecologic Oncology, Chongqing University Cancer Hospital & Chongqing Cancer Institute & Chongqing Cancer Hospital, Hanyu Road No. 181, Shapingba District, Chongqing, 400030, China.
Qian ZhengDepartment of Gynecologic Oncology, Chongqing University Cancer Hospital & Chongqing Cancer Institute & Chongqing Cancer Hospital, Hanyu Road No. 181, Shapingba District, Chongqing, 400030, China.
Ling LongSchool of Medicine, Chongqing University, Chongqing University Cancer Hospital, Chongqing, China.
Jing WangDepartment of Gynecologic Oncology, Chongqing University Cancer Hospital & Chongqing Cancer Institute & Chongqing Cancer Hospital, Hanyu Road No. 181, Shapingba District, Chongqing, 400030, China.
Dongling ZouDepartment of Gynecologic Oncology, Chongqing University Cancer Hospital & Chongqing Cancer Institute & Chongqing Cancer Hospital, Hanyu Road No. 181, Shapingba District, Chongqing, 400030, China. cqzl_zdl@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the prognostic value of magnetic resonance imaging (MRI) features and clinical features in locally advanced cervical cancer (LACC) patients after concurrent chemoradiotherapy (CCRT).

methodsA total of 189 patients with LACC who received definitive CCRT between May 2018 and December 2020 and underwent MRI, including diffusion-weighted imaging, before and 1 month after initial therapy were recruited for this study. The tumor size and mean apparent diffusion coefficient (ADC

resultsThe median follow-up time was 58 (range: 11-71) months. The 5-year PFS and OS rates were 73.8% and 85.5%, respectively. Univariate analysis revealed that the serum squamous cell carcinoma (SCC) antigen level, tumor stage, pretreatment tumor size, residual disease (RD) and post-treament ADC

conclusionElevated SCC antigen levels, advanced tumor stage, and RD size ≥ 1.1 cm were linked to worse PFS and OS. Furthermore, the ADC

Indexed as

ChemoradiotherapyUterine Cervical NeoplasmsAdultAgedDiffusion Magnetic Resonance ImagingFemaleHumansMagnetic Resonance ImagingMiddle AgedNeoplasm StagingPrognosisRetrospective StudiesTumor BurdenConcurrent chemoradiotherapyDiffusion-weighted imagingLocally advanced cervical cancerMagnetic resonance imagingResidual disease

Identifiers

PMID41039207
PMCPMC12492540

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.