Evidence map›Paper›PMID 41039092›Full record

ArticleActa neurochirurgica2025

Intraoperative integration of nTMS, CCEPs and DCS for language. A glance to the next future?

Camilla Bonaudo, Riccardo Carrai, Edoardo Pieropan, Francesca Fedi, Eleonora Visocchi, Fabrizio Baldanzi, Francesca Battista, Antonello Grippo, Alessandro Della Puppa

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In one paragraph

Article in Acta neurochirurgica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Camilla BonaudoUniveristy of Florence, Florence, Italy. camilla.bonaudo@unifi.it.
Riccardo CarraiNeurophysiopathology Unit, University Hospital of Careggi, University of Florence, Florence, Italy.
Edoardo PieropanDepartment of Information Engineering, University of Padua, Padua, Italy.
Francesca FediNeurosurgery, Department of Neuroscience, Psychology, Pharmacology and Child Health, University of Florence, University Hospital of Careggi, Florence, Italy.
Eleonora VisocchiNeurosurgery, Department of Neuroscience, Psychology, Pharmacology and Child Health, University of Florence, University Hospital of Careggi, Florence, Italy.
Fabrizio BaldanziNeurophysiopathology Unit, University Hospital of Careggi, University of Florence, Florence, Italy.
Francesca BattistaNeurosurgery, Department of Neuroscience, Psychology, Pharmacology and Child Health, University of Florence, University Hospital of Careggi, Florence, Italy.
Antonello GrippoNeurophysiopathology Unit, University Hospital of Careggi, University of Florence, Florence, Italy.
Alessandro Della PuppaUniveristy of Florence, Florence, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDirect-Cortical-Stimulation (DCS), Navigated-Transcranial Magnetic-Stimulation (nTMS), Cortico-Cortical-Evoked-Potentials (CCEPs) can be synergically used to monitor Language-network.

methodsWe illustrate a case of multimodal approach for removal of one left fronto-temporo-insular Low-Grade-Glioma.

resultsA 32-years-old female patient was operated in awake surgery (using D080-picture-naming-test). We documented a matching correspondence among frontal nTMS + spots, Penfield DCS, and CCEPs stimulation strip. The same was found in the temporal area among nTMS, DCS, and CCEPs recording strip. [Average distance among nTMS, DCS and CCEPs spots = 5.10 mm, STD = 1.08 mm. Se, PPV and Precision:100%].

conclusionsWe documented the potential utility of matching synergic technologies to preserve language.

Indexed as

Brain NeoplasmsEvoked PotentialsGliomaIntraoperative Neurophysiological MonitoringLanguageNeuronavigationTranscranial Magnetic StimulationAdultFemaleHumansAwake surgeryCortico-Cortical-Evoked-Potentials (CCEPs)Direct-Cortical-Stimulation (DCS)Intraoperative monitoring (IOM)Low-grade-glioma surgeryNavigated-Transcranial Magnetic-Stimulation (nTMS)

Identifiers

PMID41039092
PMCPMC12491366

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.