Evidence map›Paper›PMID 41039081›Full record

ArticleJournal of exposure science & environmental epidemiology2025

Collection of multimedia measurements to evaluate PFAS human exposure sources in the residential environment.

Jeffrey M Minucci, Kent Thomas, Jason D Boettger, Nicole M DeLuca, Dylan J Wallis, Peter P Egeghy, Elaine A Cohen Hubal

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Article in Journal of exposure science & environmental epidemiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jeffrey M MinucciU.S. EPA, Office of Research and Development, Research Triangle Park, NC, 27711, USA.
Kent ThomasU.S. EPA, Office of Research and Development, Research Triangle Park, NC, 27711, USA.
Jason D BoettgerORISE at U.S. EPA, Research Triangle Park, NC, 27711, USA.
Nicole M DeLucaU.S. EPA, Office of Research and Development, Research Triangle Park, NC, 27711, USA.
Dylan J WallisORISE at U.S. EPA, Research Triangle Park, NC, 27711, USA.
Peter P EgeghyU.S. EPA, Office of Research and Development, Research Triangle Park, NC, 27711, USA.
Elaine A Cohen HubalU.S. EPA, Office of Research and Development, Research Triangle Park, NC, 27711, USA. cohenhubal.elaine@epa.gov.ORCID 0000-0002-9650-3483

Funding

EPA DW-075-95955001-0
6 · The paper itself

Abstract

backgroundPer- and polyfluoroalkyl substances (PFAS) are anthropogenic chemicals with unique properties and functionality that enable multiple industrial processes and product applications. PFAS are generally persistent, widely distributed in environmental media, and linked to various adverse health effects. The primary pathway of PFAS exposure to impacted communities is through contaminated drinking water. While many studies have demonstrated exposures from contaminated drinking water in such communities, less is known about the contribution of exposure from sources within the residential environment.

objectiveMeasurement data on the nature and level of PFAS in house dust, indoor surfaces, indoor air, soil and wristbands are required to identify and understand important pathways for human exposure.

methodsIn this study, we collected house dust, surface wipe, indoor air, wristband, and soil samples at homes recruited from two communities previously impacted by drinking water contamination, one in Massachusetts and one in Delaware. At every home (n = 79), a floor dust sample was collected, while in a subset of homes (n = 28), more extensive environmental sampling was conducted. All samples collected were analyzed for up to 70 PFAS depending on the sample type.

resultsPFAS were found in all types of household samples, with 30 different PFAS detected in ≥50% of homes for at least one sample type. Vacuum dust, floor dust and soil had the highest detection rates across most PFAS. However, certain PFAS precursors were more prevalent in surface wipes, indoor air, and wristbands (e.g., FTOHs, FOSEs, FOSAs). diPAPs were widely detected across all sample types and had the highest concentrations among all analytes in dust, surface wipes and wristbands. A comparative analysis between the two sampling sites highlighted significant differences in PFAS profiles, with Delaware exhibiting higher levels of PFAAs in dust and soil, while Massachusetts showed greater concentrations of diPAPs across various media sampled. SIGNIFICANCE: These findings highlight the widespread presence of PFAS in the residential environment, and the need for mitigation strategies that address both legacy compounds and emerging precursors across numerous media. IMPACT: This study advances application of methods for sampling and measuring PFAS in the residential environment. The analysis improves our understanding of the relative importance of PFAS exposure sources in communities previously impacted by contaminated drinking water.

Indexed as

Air Pollution, IndoorEnvironmental ExposureEnvironmental MonitoringFluorocarbonsDustHousingHumansMassachusettsSoilDustFluorocarbonsSoilAqueous film-forming foam (AFFF)Contaminated soilHouse dustIndoor environmentPer- and polyfluoroalkyl substances (PFAS)

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.