ArticleEuropean journal of pediatrics2025
Comparison of lipid profiles in children with cyanotic and acyanotic heart disease.
Article in European journal of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Atherosclerosis risk in congenital heart disease (CHD) necessitates understanding lipid profiles, yet current research is inconsistent. This study compares lipid profiles in pediatric cyanotic versus acyanotic CHD, examining BMI, age, and sex influence. In this cross-sectional study, 100 children aged 1 month to 15 years who were diagnosed with CHD were enrolled from tertiary care paediatric cardiology centres. The participants were categorized into cyanotic (n = 50) and acyanotic (n = 50) groups on the basis of echocardiographic and clinical findings. Fasting (4_6 hours) venous blood samples were obtained, and serum lipid levels-including total cholesterol, triglycerides, HDL-C, and LDL-C-were measured via standardized enzymatic colorimetric assays. Statistical analysis was performed via SPSS v25 with appropriate parametric or nonparametric tests. The study revealed significantly higher triglyceride levels in the cyanotic CHD group than in the acyanotic CHD group, whereas LDL-C levels were significantly elevated in the acyanotic CHD group. Subgroup analyses demonstrated that age, sex, and body mass index significantly influenced these lipid parameters, indicating distinct metabolic profiles between the two CHD subtypes.Conclusion: The observed differences in lipid profiles between cyanotic CHD and acyanotic CHD suggest underlying pathophysiological variations that may predispose these children to early cardiovascular complications. These findings underscore the importance of early lipid screening and the development of customized preventive interventions in pediatric CHD patients.
Indexed as
Identifiers
41039074What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.