Evidence map›Paper›PMID 41038919›Full record

ArticleScientific reports2025

Assessing Teucrium polium L. from chemical profiling to antioxidant, anticancer, α-amylase, and lipase activities.

Odey Bsharat, Yousef Salama, Eman Saed, Nisreen Al-Hajj, Nawaf Al-Maharik

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. In vitro study and in silico reveal Teucrium Polium L. methanolic extract as an apoptosis inducer and a potential Bcl-2 inhibitor for breast cancer.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2026
    Article
  2. Article
  3. Fungicidal Activity of Silver Nanoparticles Synthesized Using Lithospermum erythrorhizon against Fusarium spp. In Vitro and In Planta.Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Odey BsharatDepartment of Chemistry, Faculty of Science, An-Najah National University, Nablus, 00970, Palestine.
Yousef SalamaDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, 00970, Palestine.
Eman SaedDepartment of Chemistry, Faculty of Science, An-Najah National University, Nablus, 00970, Palestine.
Nisreen Al-HajjDepartment of Chemistry, Faculty of Science, An-Najah National University, Nablus, 00970, Palestine. nalhaj@najah.edu.
Nawaf Al-MaharikDepartment of Chemistry, Faculty of Science, An-Najah National University, Nablus, 00970, Palestine. n.maharik@najah.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Teucrium polium L, known as felty germander or Palestinian Ja'adeh, primarily flourishes in Mediterranean countries such as Palestine, Jordan, and Turkey. There has been a significant increase in the investigation and analysis of essential oils derived from medicinal plants due to their potential biological and therapeutic applications. This study will investigate the chemical composition of essential oil derived from the dried leaves of T. polium L. and evaluate its in vitro antioxidant, anticancer, α-amylase, and lipase inhibitory properties. The essential oil extracted from the dried leaves of T. polium L. via hydrodistillation was analyzed using gas chromatography-mass spectrometry (GC-MS) to determine their chemical composition. Sixteen compounds were identified in the essential oil of T. polium L., with E-nerolidol (27.11%), geranyl acetone (23.26%), germacrene D (19.08%), β-caryophyllene (17.78%), α-caryophyllene (3.35%), and bicyclogermacrene (3.08%) constitute the principal components. This essential oil, abundant in oxygenated sesquiterpenes, demonstrated notable antioxidant activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) at a concentration of 20.08 ± 1.00 µg/mL. Furthermore, it exhibited significant anticancer effectiveness against the MCF-7 and B16F10 cell lines, with IC

Indexed as

alpha-AmylasesAntineoplastic AgentsAntineoplastic Agents, PhytogenicAntioxidantsLipaseOils, VolatileTeucriumCell Line, TumorGas Chromatography-Mass SpectrometryHumansPlant ExtractsPlant Leavesalpha-AmylasesAntineoplastic AgentsAntineoplastic Agents, PhytogenicAntioxidantsLipaseOils, VolatilePlant ExtractsB16F10Chemical compositionEssential oilMCF-7Medicinal plantsTeucrium polium L.

Identifiers

PMID41038919
PMCPMC12491470

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.