Evidence map›Paper›PMID 41038901›Full record

Trial reportScientific reports2025

Endoscopic sphincterotomy with balloon dilation vs. monotherapy for choledocholithiasis in periampullary diverticulum: a randomized trial.

Gong Qiong, Zhang Zhengle, Hu Yiqian, Huang Xu, Zhou Wei, Li Hanjun, Zhou Zhongyin, Tao Jing, Zhu Zhongchao

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gong Qiong *Department of Pancreatic Surgery, Renmin Hospital of Wuhan University, Wuhan, China.
Zhang Zhengle *Department of Pancreatic Surgery, Renmin Hospital of Wuhan University, Wuhan, China.
Hu YiqianDepartment of anesthesia care, Renmin Hospital of Wuhan University, Wuhan, China.
Huang XuDepartment of digestive Medicine, Renmin Hospital of Wuhan University, Wuhan, China.
Zhou WeiDepartment of digestive Medicine, Renmin Hospital of Wuhan University, Wuhan, China.
Li HanjunDepartment of Pancreatic Surgery, Renmin Hospital of Wuhan University, Wuhan, China.
Zhou ZhongyinDepartment of digestive Medicine, Renmin Hospital of Wuhan University, Wuhan, China. zhouhu0425@163.com.
Tao JingDepartment of Pancreatic Surgery, Renmin Hospital of Wuhan University, Wuhan, China. tj918@163.com.
Zhu ZhongchaoDepartment of Pancreatic Surgery, Renmin Hospital of Wuhan University, Wuhan, China. zhuzhongchao@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periampullary diverticulum (PAD) often increases the difficulty of ERCP operation, and there is no standardized treatment strategy. This study compared the efficacy of "small incision + large balloon dilation (EST + EPBD)" with traditional ERCP. 111 patients with PAD complicated with choledocholithiasis were randomly divided into experimental group (n = 55, EST < 5 mm + EPBD) and control group (n = 56, conventional EST/EPBD). The primary endpoints were one-time stone clearance and adverse event rate, while secondary endpoints included operative time and common bile duct pressure. One-time stone clearance rate: test group 98.1% vs. control group 87.5% (P = 0.029) • Mean operation time: 24 ± 9 min vs. 31 ± 11 min (P < 0.001) • CBD pressure 6 days after surgery: 11.5 ± 2.3 vs. 8.5 ± 1.6 cm H₂O (P < 0.001) • Incidence of postoperative pancreatitis: 3.6% vs. 10.7% (P = 0.206). EST + EPBD can significantly improve stone removal efficiency, shorten operation time, and may improve long-term prognosis by preserving Oddi sphincter function.

Indexed as

CholedocholithiasisDilatationDiverticulumSphincterotomy, EndoscopicAdultAgedCholangiopancreatography, Endoscopic RetrogradeFemaleHumansMaleMiddle AgedOperative TimePostoperative ComplicationsTreatment OutcomeAdverse eventCholedocholithiasisEndoscopic papillary balloon dilationEndoscopic sphincterotomyPeriampullary diverticulumPressure of the common bile duct

Identifiers

PMID41038901
PMCPMC12491501

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.