Evidence map›Paper›PMID 41038843›Full record

ArticleNature communications2025

Crotonate enhances intestinal regeneration after injury via HBO1-mediated H3K14 crotonylation.

Yanhui Xiao, Shicheng Yu, Mengxian Zhang, Nanshan Zhong, Shan Hua, Zhi Fang, Zhe Zhang, Huidong Liu, Ronghui Tan, Yuan Liu and 1 more

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yanhui Xiao *Guangzhou National Laboratory, Guangzhou, China.
Shicheng Yu *Guangzhou National Laboratory, Guangzhou, China.
Mengxian ZhangThe MOE Basic Research and Innovation Center for the Targeted Therapeutics of Solid Tumors, School of Basic Medical Sciences, Jiangxi Medical College, Nanchang University, Nanchang, China.
Nanshan ZhongThe MOE Basic Research and Innovation Center for the Targeted Therapeutics of Solid Tumors, School of Basic Medical Sciences, Jiangxi Medical College, Nanchang University, Nanchang, China.ORCID http://orcid.org/0000-0001-5299-8907
Shan HuaGuangzhou National Laboratory, Guangzhou, China.
Zhi FangThe MOE Basic Research and Innovation Center for the Targeted Therapeutics of Solid Tumors, School of Basic Medical Sciences, Jiangxi Medical College, Nanchang University, Nanchang, China.
Zhe ZhangGuangzhou National Laboratory, Guangzhou, China.
Huidong LiuThe State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China.
Ronghui TanGuangzhou National Laboratory, Guangzhou, China.
Yuan LiuThe State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China.
Ye-Guang ChenGuangzhou National Laboratory, Guangzhou, China. ygchen@tsinghua.edu.cn.ORCID http://orcid.org/0000-0002-6701-0065

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The intestinal epithelium undergoes rapid turnover driven by Lgr5

Indexed as

ColitisCrotonatesHistonesIntestinal MucosaIntestinesRegenerationAnimalsDextran SulfateMaleMiceMice, Inbred C57BLMice, KnockoutStem CellsCrotonatesDextran SulfateHistones

Identifiers

PMID41038843
PMCPMC12491526

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.