Evidence map›Paper›PMID 41038784›Full record

Observational studyGait & posture2026

Chronic neck pain is associated with altered gait performance compared to healthy controls: Cross-sectional observations.

Wren Burton, Yan Ma, Cynthia Long, Jacob McCarey, Jeffrey M Hausdorff, Robert Vining, Brad Manor, Matthew H Kowalski, Peter M Wayne

Abstract readObservational Study
In one paragraph

Observational study in Gait & posture, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wren BurtonOsher Center for Integrative Health, Brigham and Women's Hospital, Harvard Medical School, 850 Boylston St. Suite #422, Boston, MA 02445, United States; Division of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, 900 Commonwealth Ave. 3rd Floor, Boston, MA 02215, United States. Electronic address: wmburton@bwh.harvard.edu.
Yan MaOsher Center for Integrative Health, Brigham and Women's Hospital, Harvard Medical School, 850 Boylston St. Suite #422, Boston, MA 02445, United States; Division of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, 900 Commonwealth Ave. 3rd Floor, Boston, MA 02215, United States.
Cynthia LongPalmer Center for Chiropractic Research, Palmer College of Chiropractic, 1000 Brady Street, Davenport, IA 52803, United States.
Jacob McCareyPalmer Center for Chiropractic Research, Palmer College of Chiropractic, 1000 Brady Street, Davenport, IA 52803, United States.
Jeffrey M HausdorffCenter for the Study of Movement Cognition and Mobility, Floor minus 1, 13 Henrietta Szold St, Tel Aviv, Israel; Sagol School of Neuroscience and Department of Physical Therapy, Faculty of Medical and Health Sciences, Tel Aviv University, Sderot Federman, Tel Aviv-Yafo, Israel; Department of Orthopedic Surgery, Rush Alzheimer's Disease Center, Rush University Medical Center, 1653 W. Congress Parkway, Chicago, IL 60612, United States.
Robert ViningPalmer Center for Chiropractic Research, Palmer College of Chiropractic, 1000 Brady Street, Davenport, IA 52803, United States.
Brad ManorHinda and Arthur Marcus Institute for Aging Research, 1200 Centre St, Boston, MA 02131, United States.
Matthew H KowalskiOsher Center for Integrative Health, Brigham and Women's Hospital, Harvard Medical School, 850 Boylston St. Suite #422, Boston, MA 02445, United States.
Peter M WayneOsher Center for Integrative Health, Brigham and Women's Hospital, Harvard Medical School, 850 Boylston St. Suite #422, Boston, MA 02445, United States; Division of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, 900 Commonwealth Ave. 3rd Floor, Boston, MA 02215, United States.

Funding

Mass General Brigham Interdisciplinary Clinical Pain Research Training ProgramT90NS138001 · NINDS · BRIGHAM AND WOMEN'S HOSPITAL · PI ROBERT R EDWARDS, Samantha M Meints · 2024 to 2026
$1.0M
Combined Chiropractic Care and Tai Chi for Chronic Non-Specific Neck PainR34AT011368 · NCCIH · BRIGHAM AND WOMEN'S HOSPITAL · PI WAYNE, PETER MICHAEL · 2022 to 2024
$951k
Mentoring and research in mind-body and integrative therapiesK24AT009282 · NCCIH · BRIGHAM AND WOMEN'S HOSPITAL · PI WAYNE, PETER MICHAEL · 2017 to 2021
$834k
App-guided bedtime mindfulness for insomniaK23AT012475 · NCCIH · BRIGHAM AND WOMEN'S HOSPITAL · PI Yan Ma · 2024 to 2026
$517k
NCCIH NIH HHS K23 AT012475NCCIH NIH HHS K24 AT009282NCCIH NIH HHS L30 AT012557NCCIH NIH HHS R34 AT011368NINDS NIH HHS T90 NS138001
6 · The paper itself

Abstract

objectiveChronic musculoskeletal pain negatively impacts gait performance, but the impact of neck pain on gait remains unclear. This study aimed to assess measures of gait (speed and variability) in individuals with chronic neck pain (CNP) compared to non-CNP controls across various walking conditions.

methodsSixty participants with CNP and 41 controls were recruited. Pain, disability, general health, and gait were measured. Gait outcomes included gait speed, stride time variability (STV), and a multi-component gait variability index (GVI) across four different walking conditions: quiet walk, cognitive task (i.e., serial sevens test), horizontal head turning, and vertical head turning. Linear regression models were used to obtain adjusted group means, difference of means, and 95 % confidence intervals for gait outcomes. Exploratory analyses assessed the relationship between CNP intensity and gait across conditions. All models adjusted for age and sex.

resultsThe CNP group (median age: 36.5 y, 75 % female) reported more pain, disability, pain medication use, and multisite pain (p < 0.001) than controls (median age: 32 y, 61 % female). CNP participants exhibited slower gait speed (mean difference -7.0 cm/s; 95 % CI: -15.0-0.10), greater STV (mean difference 0.43 %CV; 95 % CI: 0.05-0.89), and higher GVI (mean difference 4.16; 95 % CI: 0.03-8.46). While the negative effects of pain were present across walking conditions, the magnitude varied depending on the task and outcome measure.

conclusionCNP was associated with reduced gait speed and increased variability of walking patterns. Slight variations under different dual-task conditions suggest potential relationships between pain, mobility, and cognitive-motor coordination.

Indexed as

Chronic PainGaitNeck PainAdultCase-Control StudiesCross-Sectional StudiesDisability EvaluationFemaleHumansMaleMiddle AgedPain MeasurementWalking SpeedCervicalgiaDual taskingGaitNeck painStride variability

Identifiers

PMID41038784
PMCPMC12506211

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.