Evidence map›Paper›PMID 41038619›Full record

ArticleBone & joint open2025

Hip fracture care in Zimbabwe : a cohort-based health economic analysis.

Nyashadzaishe Mafirakureva, Pauline Chido Ishumael, Tadios Manyanga, Prudance Mushayavanhu, Munyaradzi Ndekwere, Hannah Wilson, Anya Burton, Simon Graham, James Masters, Matthew L Costa and 3 more

Abstract read
In one paragraph

Article in Bone & joint open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Hip fracture care in Africa: Time for action.PLOS global public health · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Nyashadzaishe MafirakurevaSheffield Centre for Health and Related Research, School of Medicine and Population Health, University of Sheffield, Sheffield, UK.
Pauline Chido IshumaelThe Health Research Unit Zimbabwe, The Biomedical Research and Training Institute, Harare, Zimbabwe.
Tadios ManyangaThe Health Research Unit Zimbabwe, The Biomedical Research and Training Institute, Harare, Zimbabwe.
Prudance MushayavanhuDepartment of Surgery, Sally Mugabe Central Hospital, Harare, Zimbabwe.
Munyaradzi NdekwereDepartment of Surgery, Sally Mugabe Central Hospital, Harare, Zimbabwe.
Hannah WilsonMusculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Anya BurtonMusculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Simon GrahamOxford Trauma and Emergency Care, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, University of Oxford, Oxford, UK.
James MastersOxford Trauma and Emergency Care, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, University of Oxford, Oxford, UK.
Matthew L CostaOxford Trauma and Emergency Care, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, University of Oxford, Oxford, UK.
Rashida A FerrandThe Health Research Unit Zimbabwe, The Biomedical Research and Training Institute, Harare, Zimbabwe.
Celia L GregsonMusculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Sian M NoblePopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

Funding

National Institute for Health ResearchWellcomeWellcome Trust
6 · The paper itself

Abstract

Aims: Hip fractures are a leading cause of morbidity and mortality worldwide, particularly among older people. While early surgical management improves outcomes compared to non-surgical approaches, high costs of surgery pose significant barriers in low- and middle-income countries. A cost-utility analysis of hip fracture management was undertaken in Zimbabwe, to guide resource allocation and policy. Methods: Patient-level data were obtained from a prospective cohort of adults aged 40 years and above with acute hip fractures presenting to hospital in Harare (two public; five private) between October 2021 and October 2022. Healthcare resource use and costs in 2023 USD$ were assessed from individual billing data, with imputed values used for missing resources. Health outcomes were measured in quality-adjusted life-years (QALYs). Incremental cost-effectiveness ratios (ICERs), defined as the ratio of incremental costs to incremental QALYs, were estimated using a regression approach. Sensitivity analyses assessed the impact of different assumptions on cost-effectiveness. Results: The cohort had 190 patients with an average age of 72 years (SD 14.3), and 51% (n = 97) were male; 61% (n = 116) had surgery for their hip fracture. Patients who underwent surgery had 0.17 (95% CI 0.10 to 0.25) additional QALYs and incurred substantially higher healthcare costs: $1,676 (95% CI 730 to 2,621) higher per patient. The ICER for the primary analysis was $9,647/QALY gained. Restricting the analysis to patients who did not experience extensive surgical delays resulted in smaller difference in costs and an ICER of $4,126/QALY gained. The results were sensitive to the exchange rate used to estimate costs. Conclusion: Although patients who underwent surgery for hip fractures had higher costs, they had better health outcomes in terms of QALYs. Targeted improvements in provision of surgical care, particularly in minimizing surgical delays, could improve both patient outcomes and lower healthcare costs.

Identifiers

PMID41038619
PMCPMC12492040

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.