Evidence map›Paper›PMID 41037309›Full record

ArticleJAMA otolaryngology-- head & neck surgery2025

Factors Associated With Dizziness Among Patients With Vestibular Schwannoma.

Tyler Wilson, Dorina Kallogjeri, Belinda Sinks, Lauren English, Pawina Jiramongkolchai, Matthew Shew, Jacques Herzog, Craig Buchman, Jay Piccirillo, Nedim Durakovic

Abstract read
In one paragraph

Article in JAMA otolaryngology-- head & neck surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tyler WilsonDepartment of Otolaryngology-Otology and Neurotology, Washington University in St Louis, St Louis, Missouri.
Dorina KallogjeriDepartment of Otolaryngology-Otology and Neurotology, Washington University in St Louis, St Louis, Missouri.
Belinda SinksDepartment of Otolaryngology-Otology and Neurotology, Washington University in St Louis, St Louis, Missouri.
Lauren EnglishDepartment of Otolaryngology-Otology and Neurotology, Washington University in St Louis, St Louis, Missouri.
Pawina JiramongkolchaiDepartment of Otolaryngology-Otology and Neurotology, Washington University in St Louis, St Louis, Missouri.
Matthew ShewDepartment of Otolaryngology-Otology and Neurotology, Washington University in St Louis, St Louis, Missouri.
Jacques HerzogDepartment of Otolaryngology-Otology and Neurotology, Washington University in St Louis, St Louis, Missouri.
Craig BuchmanDepartment of Otolaryngology-Otology and Neurotology, Washington University in St Louis, St Louis, Missouri.
Jay PiccirilloDepartment of Otolaryngology-Otology and Neurotology, Washington University in St Louis, St Louis, Missouri.
Nedim DurakovicDepartment of Otolaryngology-Otology and Neurotology, Washington University in St Louis, St Louis, Missouri.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Importance: Patients with vestibular schwannoma (VS) commonly present with neurological symptoms such as hearing loss, tinnitus, and dizziness. However, factors associated with dizziness at presentation are not well understood. Objective: To evaluate the baseline features of adults diagnosed with VS associated with subjective dizziness using a validated instrument. Design, Setting, and Participants: This retrospective cohort study included adults with radiologically diagnosed VS who completed vestibular testing at Washington University (St Louis, Missouri) between June 2004 and January 2025. Baseline dizziness was measured using the Dizziness Handicap Inventory (DHI). Exposures: Anxiety associated with a VS diagnosis. Main Outcomes and Measures: The primary outcome was severity of dizziness based on DHI score. Results: A total of 109 patients were included; the mean (SD) age was 61 (14) years, 57 (52%) were female, and 52 (48%) were male. The mean (SD) DHI score was 27 (24) points. Participants with a history of anxiety had a DHI score that was 13.7 points (95% CI, 4.2-23.2 points) higher than those with no such history. For every additional point in severity of anxiety measured using the Generalized Anxiety Disorder-7 (GAD-7) scale, DHI score increased 2.6 points (95% CI, 2.0-3.3 points). After controlling for covariates, for every 1-point increase in GAD-7, DHI score increased by a mean of 1.9 points (95% CI, 1.3-2.6 points). On average, patients with a history of anxiety had a DHI score 10.6 points (95% CI, 2.4-18.7 points) higher than those with no such history. Conclusions and Relevance: This retrospective cohort study suggests a psychological association between anxiety and dizziness might exist among patients with VS that has not previously been explored. Further studies examining this association are needed in this patient population.

Indexed as

AnxietyDizzinessNeuroma, AcousticAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesSeverity of Illness Index

Identifiers

PMID41037309
PMCPMC12492295

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.