ArticleJACC. Case reports2025
Multivessel Spontaneous Coronary Artery Dissection Linked to Antiphospholipid Syndrome.
Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSpontaneous coronary artery dissection (SCAD) is a rare nonatherosclerotic cause of acute coronary syndrome, usually affecting young women without traditional risk factors. Currently, there is no definitive link between SCAD and autoimmune diseases such as antiphospholipid syndrome (APS). CASE SUMMARY: A 51-year-old woman presented with anterior ST-segment elevation myocardial infarction due to multivessel SCAD of the mid left anterior descending artery and an intramural hematoma in a large obtuse marginal branch. Despite conservative management and Impella support, she developed an early extension of the obtuse marginal intramural hematoma 4 days later, complicated by a left ventricular thrombus. Subsequent evaluation confirmed APS. DISCUSSION: This case illustrates multivessel SCAD with early extension in the setting of APS, highlighting critical challenges in the use of anticoagulation. Prolonged monitoring and autoimmune screening are crucial in atypical SCAD presentations. Mechanical circulatory support may assist in hemodynamic stability. TAKE-HOME MESSAGE: APS should be considered for atypical SCAD presentations, with individualized multidisciplinary management to provide optimal outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.