ArticleRespirology (Carlton, Vic.)2026
Lobe-Specific Variability in Postoperative Pulmonary Function in Lung Cancer Patients: A Longitudinal Analysis and Comparison With Traditional Predictive Models.
Article in Respirology (Carlton, Vic.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- A transfer learning-based hybrid deep- and machine-learning regression approach for predicting the postoperative pulmonary function.European radiology experimental · 2026Article
- Postoperative lung geometric repositioning after right upper lobectomy: the role of thoracic morphology configuration.Quantitative imaging in medicine and surgery · 2026Article
- Review
- Lobe-Specific Variability in Postoperative Pulmonary Function in Lung Cancer Patients: A Longitudinal Analysis and Comparison With Traditional Predictive Models.Respirology (Carlton, Vic.) · 2026Article
- AI-Assisted Volumetric Comparison of Parenchyma-Sparing Effect in Robotic Segmentectomy vs Lobectomy.JSLS : Journal of the Society of Laparoendoscopic SurgeonsArticle
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9 authors.
Funding
Abstract
BACKGROUND AND
objectiveLobectomy is the primary treatment for early-stage non-small cell lung cancer. However, pulmonary function declines postoperatively, presenting a significant challenge. This study investigated pulmonary function following lobectomy and compared these changes with predicted lung function based on the traditional segmental method, focusing on resected lobe-specific variability.
methodsThis prospective cohort study included 419 patients who underwent lobectomies for NSCLC. Pulmonary function tests measuring forced vital capacity (FVC), forced expiratory volume in one second (FEV
resultsLeft upper and right lower lobectomies demonstrated observed pulmonary function values similar to their PPOs as early as 2 weeks postoperatively. However, the other lobes declined significantly, with an approximately 25% reduction in FVC, FEV1, and DLCO, regardless of the number of segments in the lobe. Three months postoperatively, observed pulmonary function values exceeded PPO values across all lobes. Surgical approach (open vs. video-assisted thoracoscopic surgery), right upper lobectomy in the reference to right lower lobectomy, and postoperative decreased physical activity were significant factors related to the non-recovery of lung function to their PPOs at 6 months after surgery.
conclusionPostoperative pulmonary function recovery varied significantly by resected lobe, with most lobes showing better recovery than predicted postoperative values. Accurate outcome prediction requires accounting for lobe-specific characteristics and compensatory mechanisms.
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