Evidence map›Paper›PMID 41036820›Full record

ArticleClinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery2026

Development and Validation of a Prognostic Model for Persistent Hypoparathyroidism After Total or Completion Thyroidectomy.

Sam P J van Dijk, Carolien C H M Maas, Ali Alshangi, M H Elise van Driel, Eline A Feitsma, Caroline M J van Kinschot, Ivona Lončar, Charlotte van Noord, Linetta B Koppert, Schelto Kruijff and 5 more

Abstract readMulticenter StudyValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Development and Validation of a Prognostic Model for Persistent Hypoparathyroidism After Total or Completion Thyroidectomy.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Sam P J van DijkDepartment of Surgical Oncology and Gastrointestinal Surgery, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.ORCID 0000-0002-4745-7978
Carolien C H M MaasDepartment of Public Health, Erasmus University Medical Center, Rotterdam, the Netherlands.
Ali AlshangiDepartment of Surgical Oncology and Gastrointestinal Surgery, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
M H Elise van DrielDepartment of Surgical Oncology and Gastrointestinal Surgery, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Eline A FeitsmaDepartment of Surgery, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
Caroline M J van KinschotDepartment of Internal Medicine, Erasmus Medical Center Rotterdam, Rotterdam, the Netherlands.
Ivona LončarDepartment of Surgical Oncology and Gastrointestinal Surgery, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Charlotte van NoordDepartment of Internal Medicine, Maasstad Hospital Rotterdam, Rotterdam, the Netherlands.
Linetta B KoppertDepartment of Surgical Oncology and Gastrointestinal Surgery, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Schelto KruijffDepartment of Surgery, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
David van KlaverenDepartment of Public Health, Erasmus University Medical Center, Rotterdam, the Netherlands.
Cornelis VerhoefDepartment of Surgical Oncology and Gastrointestinal Surgery, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Robin P PeetersDepartment of Internal Medicine, Erasmus Medical Center Rotterdam, Rotterdam, the Netherlands.
Tessa M van GinhovenDepartment of Surgical Oncology and Gastrointestinal Surgery, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Hypoparathyroidism Study Group of the Thyroid Network

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to develop and validate a clinical prediction model to predict the occurrence of persistent hypoparathyroidism after total or completion thyroidectomy.

methodsThis multicentre retrospective cohort study included patients who underwent total or completion thyroidectomy between January 2010 and June 2021 in 12 Dutch hospitals.

resultsOf the 366 patients included, 44 (12.0%) patients developed persistent hypoparathyroidism in the first year follow-up after surgery. Multivariable logistic regression analysis showed that ΔPTH the day after surgery, corrected calcium the day after surgery, and not identifying at least one parathyroid during surgery were strong predictors for persistent hypoparathyroidism. The discriminative ability of the model was excellent (optimism-corrected C-index: 0.88, 95% CI: 0.84-0.92) with moderately calibrated predictions.

conclusionsThe model proposed in this study could be used to perform an individual assessment of patients at risk for persistent hypoparathyroidism after total thyroidectomy.

Indexed as

HypoparathyroidismPostoperative ComplicationsThyroidectomyAdultAgedCohort StudiesFemaleHumansMaleMiddle AgedNetherlandsPrognosisRetrospective Studiespersistent hypoparathyroidismprognosticationPTHreadmissions

Identifiers

PMID41036820
PMCPMC12703679

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.