ReviewCombinatorial chemistry & high throughput screening2026
Chemical Diversity of Carotenoids Derived from Aquatic Animals and their Therapeutic, Biomedical, and Natural Colorant Applications.
Review in Combinatorial chemistry & high throughput screening, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
8 authors.
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Abstract
Carotenoids, prevalent in a diverse range of aquatic animals, perform critical and multifaceted roles essential for marine and freshwater ecosystems. This review examines the distribution, biological functions, and potential biomedical applications of carotenoids sourced from various aquatic animals. Carotenoids are acquired through food consumption or metabolic pathways, playing vital roles such as photoprotection, antioxidant defense, and nutritional enhancement, particularly provitamin A. Marine sponges and cnidarians display a diverse spectrum of carotenoids, crucial for symbiosis and photoprotection. Molluscs and crustaceans exhibit varied carotenoid profiles corresponding to their trophic strategies, whereas fish and echinoderms utilize carotenoids in reproductive and developmental processes. In biomedical contexts, carotenoids act as potential anti-cancer agents and antioxidants. Lycopene, β-carotene, and astaxanthin demonstrate anti-proliferative and antioxidant effects, pivotal in cancer prevention and therapeutic interventions. Their applications extend to biomedical technologies like Raman spectroscopy and drug delivery systems, underscoring their diagnostic and therapeutic potential. Carotenoids, as powerful antioxidants, neutralize free radicals and diminish oxidative stress, which is linked to chronic diseases like cardiovascular diseases, neurodegenerative disorders, and cancer. Some carotenoids, such as beta-carotene, are precursors to vitamin A, vital for vision, immune response, and cell communication. Furthermore, carotenoids have anti-inflammatory properties that modulate inflammatory pathways and provide therapeutic potential in diseases like inflammatory bowel disease and arthritis, which are marked by chronic inflammation. Furthermore, carotenoids provide photoprotection, safeguarding the skin and other tissues from damage caused by ultraviolet radiation. This paper highlights the integral role of carotenoids in biomedical advancements, emphasizing their significance in human health research.
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Registered trials
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